Publications: Polain, Nicole

2021

Wood, A., Gurfinkel, Y., Polain, N., Lamont, W. and Rea, S.L. (2021) Molecular mechanisms underlying TDP-43 pathology in cellular and animal models of ALS and FTLD. International Journal of Molecular Sciences, 22 (9). Article 4705.

Sultana, M.A., Cluning, C., Kwong, W-S, Polain, N., Pavlos, N.J., Ratajczak, T., Walsh, J.P., Xu, J. and Rea, S.L. (2021) The SQSTM1/p62 UBA domain regulates Ajuba localisation, degradation and NF-κB signalling function. PLoS ONE, 16 (11). Art. e0259556.

Foster, A.D., Flynn, L.L., Cluning, C., Cheng, F., Davidson, J.M., Lee, A., Polain, N., Mejzini, R., Farrawell, N., Yerbury, J.J., Layfield, R., Akkari, P.A. and Rea, S.L. (2021) p62 overexpression induces TDP-43 cytoplasmic mislocalisation, aggregation and cleavage and neuronal death. Scientific Reports, 11 (1). Art. 11474.

2020

Foster, A.D., Downing, P., Figredo, E., Polain, N., Stott, A., Layfield, R. and Rea, S.L. (2020) ALS-associated TBK1 variant p.G175S is defective in phosphorylation of p62 and impacts TBK1-mediated signalling and TDP-43 autophagic degradation. Molecular and Cellular Neuroscience, 108 . Art. 103539.