Publications: Polain, Nicole

Journal Article

Gurfinkel, Y., Polain, N., Sonar, K., Nice, P., Mancera, R.L. and Rea, S.L. (2022) Functional and structural consequences of TBK1 missense variants in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Neurobiology of Disease, 174 . Art. 105859.

Wood, A., Gurfinkel, Y., Polain, N., Lamont, W. and Rea, S.L. (2021) Molecular mechanisms underlying TDP-43 pathology in cellular and animal models of ALS and FTLD. International Journal of Molecular Sciences, 22 (9). Article 4705.

Sultana, M.A., Cluning, C., Kwong, W-S, Polain, N., Pavlos, N.J., Ratajczak, T., Walsh, J.P., Xu, J. and Rea, S.L. (2021) The SQSTM1/p62 UBA domain regulates Ajuba localisation, degradation and NF-κB signalling function. PLoS ONE, 16 (11). Art. e0259556.

Foster, A.D., Flynn, L.L., Cluning, C., Cheng, F., Davidson, J.M., Lee, A., Polain, N., Mejzini, R., Farrawell, N., Yerbury, J.J., Layfield, R., Akkari, P.A. and Rea, S.L. (2021) p62 overexpression induces TDP-43 cytoplasmic mislocalisation, aggregation and cleavage and neuronal death. Scientific Reports, 11 (1). Art. 11474.

Foster, A.D., Downing, P., Figredo, E., Polain, N., Stott, A., Layfield, R. and Rea, S.L. (2020) ALS-associated TBK1 variant p.G175S is defective in phosphorylation of p62 and impacts TBK1-mediated signalling and TDP-43 autophagic degradation. Molecular and Cellular Neuroscience, 108 . Art. 103539.