Publications: Pitout, Ianthe

Journal Article

Huang, D., Thompson, J.A., Chen, S-C, Adams, A., Pitout, I., Lima, A., Zhang, D., Jeffery, R.C.H., Attia, M.S., McLaren, T.L., Lamey, T.M., De Roach, J.N., McLenachan, S., Aung-Htut, M.T., Fletcher, S., Wilton, S.D. and Chen, F.K. (2022) Characterising splicing defects of ABCA4 variants within exons 13–50 in patient-derived fibroblasts. Experimental Eye Research, 225 . Art. 109276.

Flynn, L.L., Li, R., Pitout, I.L., Aung-Htut, M.T., Larcher, L.M., Cooper, J.A.L., Greer, K.L., Hubbard, A., Griffiths, L., Bond, C.S., Wilton, S.D., Fox, A.H. and Fletcher, S. (2022) Single stranded fully Modified-Phosphorothioate oligonucleotides can induce structured nuclear inclusions, alter nuclear protein localization and disturb the transcriptome In Vitro. Frontiers in Genetics, 13 . Art. 791416.

Grainok, J., Pitout, I., Wilton, S., Chen, F.K., Mitrpant, C. and Fletcher, S. (2021) Modulation of CNOT3 expression using antisense oligomers to treat retinitis pigmentosa 11. Investigative Ophthalmology and Visual Science, 62 (8). Article 1181.

Flynn, L.L., Mitrpant, C., Adams, A., Pitout, I.L., Stirnweiss, A., Fletcher, S. and Wilton, S.D. (2021) Targeted SMN exon skipping: A useful control to assess in vitro and in vivo splice-switching studies. Biomedicines, 9 (5). Article 552.

Pytte, J., Anderton, R.S., Flynn, L.L., Theunissen, F., Jiang, L., Pitout, I., James, I., Mastaglia, F.L., Saunders, A.M., Bedlack, R., Siddique, T., Siddique, N. and Akkari, P.A. (2020) Association of a structural variant within the SQSTM1 gene with amyotrophic lateral sclerosis. Neurology Genetics, 6 (2). Art. e406.

Mejzini, R., Flynn, L.L., Pitout, I.L., Fletcher, S., Wilton, S.D. and Akkari, P.A. (2019) ALS genetics, mechanisms, and therapeutics: Where are we now? Frontiers in Neuroscience, 13 .

Pitout, I., Flynn, L.L., Wilton, S.D. and Fletcher, S. (2019) Antisense-mediated splice intervention to treat human disease: the odyssey continues. F1000Research, 8 .

Aung-Htut, M.T., McIntosh, C.S., Ham, K.A.ORCID: 0000-0002-7036-5334, Pitout, I.L., Flynn, L.L., Greer, K., Fletcher, S. and Wilton, S.D. (2019) Systematic approach to developing splice modulating antisense oligonucleotides. International Journal of Molecular Sciences, 20 (20). Article 5030.

Flynn, L.L., Mitrpant, C., Pitout, I.L., Fletcher, S. and Wilton, S.D. (2018) Antisense oligonucleotide mediated terminal intron retention of the SMN2 transcript. Molecular Therapy - Nucleic Acids, 11 . pp. 91-102.

Pitout, I., Fletcher, S., Etherington, S.ORCID: 0000-0002-6589-8793 and Wilton, S. (2015) A spanner in the works of human transformer 2 β1 autoregulation may reduce the severity of spinal muscular atrophy. The Journal of Gene Medicine, 17 (8 - 9). pp. 173-217.

Conference Item

Pitout, I., Fletcher, S., Etherington, S.ORCID: 0000-0002-6589-8793 and Wilton, S. (2015) A spanner in the works of human Transformer-2-β1 autoregulation may reduce the severity of spinal muscular atrophy. In: 9th Australasian Gene and Cell Therapy Society meeting, 29 April - 1 May, Parkville, Victoria, Australia.

Thesis

Pitout, Ianthe (2018) Modulation of modifiers of Pre-mRNA splicing: A therapeutic strategy for Amenable Inherited Diseases. PhD thesis, Murdoch University.