Publications: Le, Bao
2019
Chen, S., Le, B.T., Chakravarthy, M., Kosbar, T.R. and Veedu, R.N. (2019) Systematic evaluation of 2′-Fluoro modified chimeric antisense oligonucleotide-mediated exon skipping in vitro. Scientific Reports, 9 (1). Article number 6078.
2018
Le, B.T., Raguraman, P., Kosbar, T.R., Fletcher, S., Wilton, S.D. and Veedu, R.N. (2018) Antisense oligonucleotides targeting angiogenic factors as potential cancer therapeutics. Molecular Therapy - Nucleic Acids, 14 (1). pp. 142-157.
Le, Bao Tri (2018) Development of novel chemically-modified splice-modulating antisense oligonucleotides for tackling Duchenne muscular dystrophy and solid cancers. PhD thesis, Murdoch University.
Kokil, G.R., Veedu, R.N., Le, B.T., Ramm, G.A. and Parekh, H.S. (2018) Self-assembling asymmetric peptide-dendrimer micelles – a platform for effective and versatile in vitro nucleic acid delivery. Scientific Reports, 8 (1).
Le, B.T., Hughes, Q., Rakesh, S., Baker, R., Jørgensen, P.T., Wengel, J. and Veedu, R.N. (2018) Unlocked nucleic acid modified primer-based enzymatic polymerization assay: Towards allele-specific genotype detection of human platelet antigens. RSC Advances, 8 (57). pp. 32770-32774.
2017
Le, B.T., Murayama, K., Shabanpoor, F., Asanuma, H. and Veedu, R.N. (2017) Antisense oligonucleotide modified with serinol nucleic acid (SNA) induces exon skipping in mdx myotubes. RSC Advances, 7 (54). pp. 34049-34052.
Hughes, Q., Le, B.T., Gilmore, G., Baker, R. and Veedu, R. (2017) Construction of a bivalent thrombin binding aptamer and its antidote with improved properties. Molecules, 22 (10).
Chakravarthy, M., Aung-Htut, M.T., Le, B.T. and Veedu, R.N. (2017) Novel Chemically-modified DNAzyme targeting Integrin alpha-4 RNA transcript as a potential molecule to reduce inflammation in multiple sclerosis. Scientific Reports, 7 (1).
Le, B.T., Hornum, M., Sharma, P.K., Nielsen, P. and Veedu, R.N. (2017) Nucleobase-modified antisense oligonucleotides containing 5-(phenyltriazol)-2′-deoxyuridine nucleotides induce exon-skipping in vitro. RSC Advances, 7 (86). pp. 54542-54545.
Le, B.T., Adams, A.M., Fletcher, S., Wilton, S.D. and Veedu, R.N. (2017) Rational design of short locked Nucleic Acid-Modified 2′- O -Methyl antisense oligonucleotides for efficient exon-skipping in vitro. Molecular Therapy - Nucleic Acids, 9 . pp. 155-161.
2016
Le, B.T., Chen, S., Abramov, M., Herdewijn, P. and Veedu, R.N. (2016) Evaluation of anhydrohexitol nucleic acid, cyclohexenyl nucleic acid and d-altritol nucleic acid-modified 2′-O-methyl RNA mixmer antisense oligonucleotides for exon skipping in vitro. Chemical Communications, 52 (92). pp. 13467-13470.
Le, B.T., Filichev, V.V. and Veedu, R.N. (2016) Investigation of twisted intercalating nucleic acid (TINA)-modified antisense oligonucleotides for splice modulation by induced exon-skipping in vitro. RSC Advances, 6 (97). pp. 95169-95172.
Chen, S., Le, B.T., Rahimizadeh, K., Shaikh, K., Mohal, N. and Veedu, R.N. (2016) Synthesis of a morpholino nucleic acid (MNA)-Uridine phosphoramidite, and exon skipping using MNA/2′-O-Methyl mixmer antisense oligonucleotide. Molecules, 21 (11). p. 1582.
