Publications: Le, Bao

Journal Article

Le, B.T., Paul, S., Jastrzebska, K., Langer, H., Caruthers, M.H. and Veedu, R.N. (2022) Thiomorpholino oligonucleotides as a robust class of next generation platforms for alternate mRNA splicing. Proceedings of the National Academy of Sciences, 119 (36). Art. e2207956119.

Le, B.T., Agarwal, S. and Veedu, R.N. (2021) Evaluation of DNA segments in 2′-modified RNA sequences in designing efficient splice switching antisense oligonucleotides. RSC Advances, 11 (23). pp. 14029-14035.

Chen, S., Le, B.T., Chakravarthy, M., Kosbar, T.R. and Veedu, R.N. (2020) Author Correction: Systematic evaluation of 2′-Fluoro modified chimeric antisense oligonucleotide-mediated exon skipping in vitro. Scientific Reports, 10 (1). Art. 6669.

Le, B.T., Kosbar, T.R. and Veedu, R.N. (2020) Novel disulfide-bridged bioresponsive antisense oligonucleotide induces efficient splice modulation in muscle Myotubes in Vitro. ACS Omega, 5 (29). pp. 18035-18039.

Chen, S., Le, B.T., Chakravarthy, M., Kosbar, T.R. and Veedu, R.N. (2019) Systematic evaluation of 2′-Fluoro modified chimeric antisense oligonucleotide-mediated exon skipping in vitro. Scientific Reports, 9 (1). Article number 6078.

Le, B.T., Raguraman, P., Kosbar, T.R., Fletcher, S., Wilton, S.D. and Veedu, R.N. (2018) Antisense oligonucleotides targeting angiogenic factors as potential cancer therapeutics. Molecular Therapy - Nucleic Acids, 14 (1). pp. 142-157.

Kokil, G.R., Veedu, R.N., Le, B.T., Ramm, G.A. and Parekh, H.S. (2018) Self-assembling asymmetric peptide-dendrimer micelles – a platform for effective and versatile in vitro nucleic acid delivery. Scientific Reports, 8 (1).

Le, B.T., Hughes, Q., Rakesh, S., Baker, R., Jørgensen, P.T., Wengel, J. and Veedu, R.N. (2018) Unlocked nucleic acid modified primer-based enzymatic polymerization assay: Towards allele-specific genotype detection of human platelet antigens. RSC Advances, 8 (57). pp. 32770-32774.

Le, B.T., Murayama, K., Shabanpoor, F., Asanuma, H. and Veedu, R.N. (2017) Antisense oligonucleotide modified with serinol nucleic acid (SNA) induces exon skipping in mdx myotubes. RSC Advances, 7 (54). pp. 34049-34052.

Hughes, Q., Le, B.T., Gilmore, G., Baker, R. and Veedu, R. (2017) Construction of a bivalent thrombin binding aptamer and its antidote with improved properties. Molecules, 22 (10).

Chakravarthy, M., Aung-Htut, M.T., Le, B.T. and Veedu, R.N. (2017) Novel Chemically-modified DNAzyme targeting Integrin alpha-4 RNA transcript as a potential molecule to reduce inflammation in multiple sclerosis. Scientific Reports, 7 (1).

Le, B.T., Hornum, M., Sharma, P.K., Nielsen, P. and Veedu, R.N. (2017) Nucleobase-modified antisense oligonucleotides containing 5-(phenyltriazol)-2′-deoxyuridine nucleotides induce exon-skipping in vitro. RSC Advances, 7 (86). pp. 54542-54545.

Le, B.T., Adams, A.M., Fletcher, S., Wilton, S.D. and Veedu, R.N. (2017) Rational design of short locked Nucleic Acid-Modified 2′- O -Methyl antisense oligonucleotides for efficient exon-skipping in vitro. Molecular Therapy - Nucleic Acids, 9 . pp. 155-161.

Le, B.T., Chen, S., Abramov, M., Herdewijn, P. and Veedu, R.N. (2016) Evaluation of anhydrohexitol nucleic acid, cyclohexenyl nucleic acid and d-altritol nucleic acid-modified 2′-O-methyl RNA mixmer antisense oligonucleotides for exon skipping in vitro. Chemical Communications, 52 (92). pp. 13467-13470.

Le, B.T., Filichev, V.V. and Veedu, R.N. (2016) Investigation of twisted intercalating nucleic acid (TINA)-modified antisense oligonucleotides for splice modulation by induced exon-skipping in vitro. RSC Advances, 6 (97). pp. 95169-95172.

Chen, S., Le, B.T., Rahimizadeh, K., Shaikh, K., Mohal, N. and Veedu, R.N. (2016) Synthesis of a morpholino nucleic acid (MNA)-Uridine phosphoramidite, and exon skipping using MNA/2′-O-Methyl mixmer antisense oligonucleotide. Molecules, 21 (11). p. 1582.

Thesis

Le, Bao Tri (2018) Development of novel chemically-modified splice-modulating antisense oligonucleotides for tackling Duchenne muscular dystrophy and solid cancers. PhD thesis, Murdoch University.