Publications: Holmes, Elaine

Journal Article

Kadyrov, M., Whiley, L.ORCID: 0000-0002-9088-4799, Brown, B.ORCID: 0000-0001-7927-2540, Erickson, K.I. and Holmes, E. (2022) Associations of the lipidome with ageing, cognitive decline and exercise behaviours. Metabolites, 12 (9). Article 822.

Loo, R.L., Chan, Q., Nicholson, J.K. and Holmes, E. (2022) Balancing the Equation: A Natural History of Trimethylamine and Trimethylamine-N-oxide. Journal of Proteome Research, 21 (3). pp. 560-589.

Chan, Q., Wren, G.M., Lau, C-H.E., Ebbels, T.M.D., Gibson, R., Loo, R.L., Aljuraiban, G.S., Posma, J.M., Dyer, A.R., Steffen, L.M., Rodriguez, B.L., Appel, L.J., Daviglus, M.L., Elliott, P., Stamler, J., Holmes, E. and Van Horn, L. (2022) Blood pressure interactions with the DASH dietary pattern, sodium, and potassium: The International Study of Macro-/Micronutrients and Blood Pressure (INTERMAP). The American Journal of Clinical Nutrition, 116 (1). pp. 216-229.

Brignardello, J., Fountana, S., Posma, J.M., Chambers, E.S., Nicholson, J.K., Wist, J., Frost, G., Garcia-Perez, I. and Holmes, E. (2022) Characterization of diet-dependent temporal changes in circulating short-chain fatty acid concentrations: A randomized crossover dietary trial. The American Journal of Clinical Nutrition .

Nitschke, P., Lodge, S., Hall, D., Schaefer, H., Spraul, M., Embade, N., Millet, O., Holmes, E., Wist, J. and Nicholson, J.K. (2022) Direct low field J-edited diffusional proton NMR spectroscopic measurement of COVID-19 inflammatory biomarkers in human serum. The Analyst, 147 (19). pp. 4213-4221.

Yau, A., Fear, M.W., Gray, N., Ryan, M., Holmes, E., Nicholson, J.K., Whiley, L.ORCID: 0000-0002-9088-4799 and Wood, F.M. (2022) Enhancing the accuracy of surgical wound excision following burns trauma via application of Rapid Evaporative IonisationMass Spectrometry (REIMS). Burns, 48 (7). pp. 1574-1583.

Gutiérrez, C.F., Rodríguez-Romero, N., Egan, S.ORCID: 0000-0003-4395-4069, Holmes, E. and Sanabria, J. (2022) Exploiting the potential of bioreactors for creating spatial organization in the soil microbiome: A strategy for increasing sustainable agricultural practices. Microorganisms, 10 (7). Article 1464.

Masuda, R., Lodge, S., Whiley, L.ORCID: 0000-0002-9088-4799, Gray, N., Lawler, N., Nitschke, P., Bong, S-H, Kimhofer, T., Loo, R.L., Boughton, B.ORCID: 0000-0001-6342-9814, Zeng, A.X., Hall, D., Schaefer, H., Spraul, M., Dwivedi, G., Yeap, B.B., Diercks, T., Bernardo-Seisdedos, G., Mato, J.M., Lindon, J.C., Holmes, E., Millet, O., Wist, J. and Nicholson, J.K. (2022) Exploration of human serum lipoprotein supramolecular phospholipids using statistical heterospectroscopy in n-Dimensions (SHY-n): Identification of potential cardiovascular risk biomarkers related to SARS-CoV-2 infection. Analytical Chemistry, 94 (10). pp. 4426-4436.

Mujagic, Z., Kasapi, M., Jonkers, D.M., Garcia-Perez, I., Vork, L., Weerts, Z.Z.R.M., Serrano-Contreras, J.I., Zhernakova, A., Kurilshikov, A., Scotcher, J., Holmes, E., Wijmenga, C., Keszthelyi, D., Nicholson, J.K., Posma, J.M and Masclee, A.A. (2022) Integrated fecal microbiome–metabolome signatures reflect stress and serotonin metabolism in irritable bowel syndrome. Gut Microbes, 14 (1). Art. e2063016.

Nitschke, P., Lodge, S., Kimhofer, T., Masuda, R., Bong, S-H, Hall, D., Schäfer, H., Spraul, M., Pompe, N., Diercks, T., Bernardo-Seisdedos, G., Mato, J.M., Millet, O., Susic, D., Henry, A., El-Omar, E.M., Holmes, E., Lindon, J.C., Nicholson, J.K. and Wist, J. (2022) J-Edited diffusional proton nuclear magnetic resonance spectroscopic measurement of glycoprotein and supramolecular phospholipid biomarkers of inflammation in human serum. Analytical Chemistry, 94 (2). pp. 1333-1341.

Dehghan, A., Pinto, R.C., Karaman, I., Huang, J., Durainayagam, B.R., Ghanbari, M., Nazeer, A., Zhong, Q., Liggi, S., Whiley, L.ORCID: 0000-0002-9088-4799, Mustafa, R., Kivipelto, M., Solomon, A., Ngandu, T., Kanekiyo, T., Aikawa, T., Radulescu, C.I., Barnes, S.J., Graça, G., Chekmeneva, E., Camuzeaux, S., Lewis, M.R., Kaluarachchi, M.R., Ikram, M.A., Holmes, E., Tzoulaki, I., Matthews, P.M., Griffin, J.L. and Elliott, P. (2022) Metabolome-wide association study on ABCA7 indicates a role of ceramide metabolism in Alzheimer’s disease. Proceedings of the National Academy of Sciences, 119 (43). Art. e2206083119.

Penney, N.C., Yeung, D.K.T., Garcia-Perez, I., Posma, J.M., Kopytek, A., Garratt, B., Ashrafian, H., Frost, G., Marchesi, J.R., Purkayastha, S., Hoyles, L., Darzi, A. and Holmes, E. (2022) Multi-omic phenotyping reveals host-microbe responses to bariatric surgery, glycaemic control and obesity. Communications Medicine, 2 (1). Art. 127.

U, M.R.A., Shen, E.Y-L, Cartlidge, C., Alkhatib, A., Thursz, M.R., Waked, I., Gomaa, A.I., Holmes, E., Sharma, R. and Taylor-Robinson, S.D. (2022) Optimized systematic review tool: Application to candidate biomarkers for the diagnosis of hepatocellular carcinoma. Cancer Epidemiology, Biomarkers & Prevention, 31 (7). pp. 1261-1274.

Sanabria, J., Egan, S.ORCID: 0000-0003-4395-4069, Masuda, R., Lee, A.J., Gibson, G.R., Nicholson, J.K., Wist, J. and Holmes, E. (2022) Overview of the nomenclature and network of contributors to the development of bioreactors for human gut simulation using bibliometric tools: A fragmented landscape. Journal of Agricultural and Food Chemistry, 70 (37). pp. 11458-11467.

Yeung, K., Penney, N., Whiley, L.ORCID: 0000-0002-9088-4799, Ashrafian, H., Purkayastha, S., Holmes, E. and Darzi, A. (2022) Serum amino acid ratios as proxies to mechanisms contributing to improved metabolic health after bariatric surgery: Basic science and research in bariatric surgery. Obesity Surgery, 32 (S2). p. 483.

Yeung, K., Whiley, L.ORCID: 0000-0002-9088-4799, Penney, N., Ashrafian, H., Purkayastha, S., Darzi, A. and Holmes, E. (2022) Serum lipidomic signatures of type 2 diabetes and early surgical diabetes resolution: Basic science and research in bariatric surgery. Obesity Surgery, 32 (S2). p. 485.

Begum, S., Johnson, B.Z., Morillon, A-C, Yang, R.ORCID: 0000-0003-2563-2015, Bong, S-H, Whiley, L.ORCID: 0000-0002-9088-4799, Gray, N., Fear, V.S., Cuttle, L., Holland, A.J.A., Nicholson, J.K., Wood, F.M., Fear, M.W. and Holmes, E. (2022) Systemic long-term metabolic effects of acute non-severe paediatric burn injury. Scientific Reports, 12 (1). Art. 13043.

Yeung, K.T.D., Penney, N., Whiley, L.ORCID: 0000-0002-9088-4799, Ashrafian, H., Lewis, M.R., Purkayastha, S., Darzi, A. and Holmes, E. (2022) The impact of bariatric surgery on serum tryptophan–kynurenine pathway metabolites. Scientific Reports, 12 (1). Art. 294.

Posma, J.M., Garcia-Perez, I., Frost, G., Aljuraiban, G.S., Chan, Q., Van Horn, L., Daviglus, M., Stamler, J., Holmes, E., Elliott, P. and Nicholson, J.K. (2021) Author Correction: Nutriome–metabolome relationships provide insights into dietary intake and metabolism. Nature Food .

Gray, N., Lawler, N., Zeng, A., Ryan, M., Bong, S-H, Boughton, B.ORCID: 0000-0001-6342-9814, Bizkarguenaga, M., Bruzzone, C., Embade, N., Wist, J., Holmes, E., Millet, O., Nicholson, J. and Whiley, L.ORCID: 0000-0002-9088-4799 (2021) Diagnostic potential of the plasma lipidome in infectious disease: Application to acute SARS-CoV-2 infection. Metabolites, 11 (7). Article 467.

Lodge, S., Nitschke, P., Kimhofer, T., Wist, J., Bong, S-H, Loo, R.L., Masuda, R., Begum, S., Richards, T., Lindon, J.C., Bermel, W., Reinsperger, T., Schaefer, H., Spraul, M., Holmes, E. and Nicholson, J.K. (2021) Diffusion and relaxation edited Proton NMR Spectroscopy of plasma reveals a High-Fidelity supramolecular biomarker signature of SARS-CoV-2 infection. Analytical Chemistry, 93 (8). pp. 3976-3986.

Holmes, E., Wist, J., Masuda, R., Lodge, S., Nitschke, P., Kimhofer, T., Loo, R.L., Begum, S., Boughton, B.ORCID: 0000-0001-6342-9814, Yang, R.ORCID: 0000-0003-2563-2015, Morillon, A-C, Chin, S-T, Hall, D., Ryan, M., Bong, S-H, Gay, M., Edgar, D.W., Lindon, J.C., Richards, T., Yeap, B.B., Pettersson, S., Spraul, M., Schaefer, H., Lawler, N.G., Gray, N., Whiley, L.ORCID: 0000-0002-9088-4799 and Nicholson, J.K. (2021) Incomplete systemic recovery and metabolic phenoreversion in Post-Acute-Phase nonhospitalized COVID-19 Patients: Implications for assessment of Post-Acute COVID-19 syndrome. Journal of Proteome Research, 20 (6). pp. 3315-3329.

Mujagic, Z., Kasapi, M., Jonkers, D.M., Garcia-Perez, I., Weerts, Z.Z.R.M., Vork, L., Serrano-Contreras, J-I, Zhernakova, A., Kurilshikov, A., Holmes, E., Keszthelyi, D., Nicholson, J.K., Posma, J.M., Masclee, A.A. and Wijmenga, C. (2021) Integrated faecal microbiome-metabolome signatures reflect stress and serotonin metabolism in Irritable Bowel Syndrome. Neurogastroenterology and motility, 33 (Supp. 2). Art. 745290.

Masuda, R., Lodge, S., Nitschke, P., Spraul, M., Schaefer, H., Bong, S-H, Kimhofer, T., Hall, D., Loo, R.L., Bizkarguenaga, M., Bruzzone, C., Gil-Redondo, R., Embade, N., Mato, J.M., Holmes, E., Wist, J., Millet, O. and Nicholson, J.K. (2021) Integrative modeling of plasma metabolic and lipoprotein biomarkers of SARS-CoV-2 infection in Spanish and Australian COVID-19 patient cohorts. Journal of Proteome Research, 20 (8). pp. 4139-4152.

Lodge, S., Nitschke, P., Loo, R.L., Kimhofer, T., Bong, S-H, Richards, T., Begum, S., Spraul, M., Schaefer, H., Lindon, J.C., Holmes, E. and Nicholson, J.K. (2021) Low volume in Vitro diagnostic proton NMR Spectroscopy of human blood plasma for lipoprotein and metabolite analysis: Application to SARS-CoV-2 biomarkers. Journal of Proteome Research, 20 (2). pp. 1415-1423.

Whiley, L.ORCID: 0000-0002-9088-4799, Chappell, K.E., D’Hondt, E., Lewis, M.R., Jiménez, B., Snowden, S.G., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Swann, J.R., Hye, A., Lovestone, S., Legido-Quigley, C. and Holmes, E. (2021) Metabolic phenotyping reveals a reduction in the bioavailability of serotonin and kynurenine pathway metabolites in both the urine and serum of individuals living with Alzheimer’s disease. Alzheimer's Research & Therapy, 13 (1). Art. 20.

Lodge, S., Nitschke, P., Kimhofer, T., Coudert, J.D., Begum, S., Bong, S-H, Richards, T., Edgar, D., Raby, E., Spraul, M., Schaefer, H., Lindon, J.C., Loo, R.L., Holmes, E. and Nicholson, J.K. (2021) NMR spectroscopic windows on the systemic effects of SARS-CoV-2 infection on plasma lipoproteins and metabolites in relation to circulating cytokines. Journal of Proteome Research, 20 (2). pp. 1382-1396.

Jiménez, B., Abellona U, M.R., Drymousis, P., Kyriakides, M., Clift, A.K., Liu, D.S.K., Rees, E., Holmes, E., Nicholson, J.K., Kinross, J.M. and Frilling, A. (2021) Neuroendocrine neoplasms: Identification of novel metabolic circuits of potential diagnostic utility. Cancers, 13 (3). Art. 374.

Seyfried, F., Phetcharaburanin, J., Glymenaki, M., Nordbeck, A., Hankir, M., Nicholson, J.K., Holmes, E., Marchesi, J.R. and Li, J.V. (2021) Roux-en-Y gastric bypass surgery in Zucker rats induces bacterial and systemic metabolic changes independent of caloric restriction-induced weight loss. Gut Microbes, 13 (1). pp. 1-20.

Li, J.V., Ashrafian, H., Sarafian, M., Homola, D., Rushton, L., Barker, G., Cabrera, P.M., Lewis, M.R., Darzi, A., Lin, E., Gletsu-Miller, N.A., Atkin, S.L., Sathyapalan, T., Gooderham, N.J., Nicholson, J.K., Marchesi, J.R., Athanasiou, T. and Holmes, E. (2021) Roux-en-Y gastric bypass-induced bacterial perturbation contributes to altered host-bacterial co-metabolic phenotype. Microbiome, 9 (1). Art. 139.

Blaise, B.J., Correia, G.D.S., Haggart, G.A., Surowiec, I., Sands, C., Lewis, M.R., Pearce, J.T.M., Trygg, J., Nicholson, J.K., Holmes, E. and Ebbels, T.M.D. (2021) Statistical analysis in metabolic phenotyping. Nature Protocols .

Lawler, N.G., Gray, N., Kimhofer, T., Boughton, B.ORCID: 0000-0001-6342-9814, Gay, M., Yang, R.ORCID: 0000-0003-2563-2015, Morillon, A-C, Chin, S-T, Ryan, M., Begum, S., Bong, S-H, Coudert, J.D., Edgar, D., Raby, E., Pettersson, S., Richards, T., Holmes, E., Whiley, L.ORCID: 0000-0002-9088-4799 and Nicholson, J.K. (2021) Systemic perturbations in amine and kynurenine metabolism associated with acute SARS-CoV-2 infection and inflammatory cytokine responses. Journal of Proteome Research, 20 (5). pp. 2796-2811.

Wei, G.Z., Martin, K.A., Xing, P.Y., Agrawal, R., Whiley, L.ORCID: 0000-0002-9088-4799, Wood, T.K., Hejndorf, S., Ng, Y.Z., Low, J.Z.Y., Rossant, J., Nechanitzky, R., Holmes, E., Nicholson, J.K., Tan, E-K, Matthews, P.M. and Pettersson, S. (2021) Tryptophan-metabolizing gut microbes regulate adult neurogenesis via the aryl hydrocarbon receptor. Proceedings of the National Academy of Sciences, 118 (27). Art. e2021091118.

Posma, J.M., Stamler, J., Garcia-Perez, I., Chan, Q., Wijeyesekera, A., Daviglus, M., Van Horn, L., Holmes, E., Nicholson, J. and Elliott, P. (2021) Urinary metabolic phenotype of blood pressure. Journal of Hypertension, 39 (Supp.1). e70.

Papamichou, D., Panagiotakos, D.B., Holmes, E., Koutsakis, P.ORCID: 0000-0002-4168-0888, Katsoulotos, H., Loo, R.L. and Itsiopoulos, C. (2021) The rationale and design of a Mediterranean diet accompanied by time restricted feeding to optimise the management of type 2 diabetes: the MedDietFast randomised controlled trial. Nutrition, Metabolism and Cardiovascular Diseases, 32 (1). pp. 220-230.

Gray, N., Lawler, N.G., Yang, R.ORCID: 0000-0003-2563-2015, Morillon, A-C, Gay, M.C.L., Bong, S-H, Holmes, E., Nicholson, J.K. and Whiley, L.ORCID: 0000-0002-9088-4799 (2021) A simultaneous exploratory and quantitative amino acid and biogenic amine metabolic profiling platform for rapid disease phenotyping via UPLC-QToF-MS. Talanta, 223 (Pt. 2). Article 121872.

James, K., Bottacini, F., Contreras, J.I.S., Vigoureux, M., Egan, M., Motherway, M.O., Holmes, E. and van Sinderen, D. (2020) Author Correction: Metabolism of the predominant human milk oligosaccharide fucosyllactose by an infant gut commensal. Scientific Reports, 10 (1). Art. 17265.

Garcia-Perez, I., Posma, J.M., Serrano-Contreras, J.I., Boulangé, C.L., Chan, Q., Frost, G., Stamler, J., Elliott, P., Lindon, J.C., Holmes, E. and Nicholson, J.K. (2020) Identifying unknown metabolites using NMR-based metabolic profiling techniques. Nature Protocols, 15 . pp. 2538-2567.

Vonhof, E.V., Piotto, M., Holmes, E., Lindon, J.C., Nicholson, J.K. and Li, J.V. (2020) Improved spatial resolution of metabolites in tissue biopsies using high-resolution Magic-Angle-Spinning slice localization NMR spectroscopy. Analytical Chemistry, 92 (17). pp. 11516-11519.

Kimhofer, T., Lodge, S., Whiley, L.ORCID: 0000-0002-9088-4799, Gray, N., Loo, R.L., Lawler, N.G., Nitschke, P., Bong, S-H, Morrison, D.L., Begum, S., Richards, T., Yeap, B.B., Smith, C., Smith, K.G.C., Holmes, E. and Nicholson, J.K. (2020) Integrative modeling of quantitative plasma lipoprotein, metabolic, and amino acid data reveals a multiorgan pathological signature of SARS-CoV-2 infection. Journal of Proteome Research, 19 (11). pp. 4442-4454.

West, K.A., Kanu, C., Maric, T., McDonald, J.A.K., Nicholson, J.K., Li, J.V., Johnson, M.R, Holmes, E. and Savvidou, M.D. (2020) Longitudinal metabolic and gut bacterial profiling of pregnant women with previous bariatric surgery. Gut, 69 (8). pp. 1452-1459.

Lau, C.-H.E., Taylor-Bateman, V., Vorkas, P.A., Graça, G., Vu, T.-H.T., Hou, L., Chekmeneva, E., Ebbels, T.M.D., Chan, Q., Van Horn, L. and Holmes, E. (2020) Metabolic signatures of gestational weight gain and postpartum weight loss in a lifestyle intervention study of overweight and obese women. Metabolites, 10 (12). Article 498.

Gallagher, K., Catesson, A., Griffin, J.L., Holmes, E. and Williams, H.R.T. (2020) Metabolomic Analysis in Inflammatory Bowel Disease: A Systematic Review. Journal of Crohn's and Colitis, 15 (5). pp. 813-826.

Ding, N.S., McDonald, J.A.K., Perdones-Montero, A., Rees, D.N., Adegbola, S.O., Misra, R., Hendy, P., Penez, L., Marchesi, J.R., Holmes, E., Sarafian, M.H. and Hart, A.L. (2020) Metabonomics and the gut microbiome associated with primary response to Anti-TNF therapy in Crohn’s Disease. Journal of Crohn's and Colitis, 14 (8). pp. 1090-1102.

Posma, J.M., Garcia-Perez, I., Frost, G., Aljuraiban, G.S., Chan, Q., Van Horn, L., Daviglus, M., Stamler, J., Holmes, E., Elliott, P. and Nicholson, J.K. (2020) Nutriome–metabolome relationships provide insights into dietary intake and metabolism. Nature Food, 1 (7). pp. 426-436.

Loo, R.L., Lodge, S., Kimhofer, T., Bong, S-H, Begum, S., Whiley, L.ORCID: 0000-0002-9088-4799, Gray, N., Lindon, J.C., Nitschke, P., Lawler, N.G., Schäfer, H., Spraul, M., Richards, T., Nicholson, J.K. and Holmes, E. (2020) Quantitative in-vitro diagnostic NMR spectroscopy for lipoprotein and metabolite measurements in plasma and serum: Recommendations for analytical artifact minimization with special reference to COVID-19/SARS-CoV-2 Samples. Journal of Proteome Research, 19 (11). pp. 4428-4441.

Loo, R.L., Chan, Q., Antti, H., Li, J.V., Ashrafian, H., Elliott, P., Stamler, J., Nicholson, J.K., Holmes, E., Wist, J. and Wren, J. (2020) Strategy for improved characterization of human metabolic phenotypes using a COmbined Multi-block principal components analysis with statistical spectroscopy (COMPASS). Bioinformatics, 36 (21). pp. 5229-5236.

Martinez-Gili, L., McDonald, J.A.K., Liu, Z., Kao, D., Allegretti, J.R., Monaghan, T.M., Barker, G.F., Miguéns Blanco, J., Williams, H.R.T., Holmes, E., Thursz, M.R., Marchesi, J.R. and Mullish, B.H. (2020) Understanding the mechanisms of efficacy of fecal microbiota transplant in treating recurrent Clostridioides difficile infection and beyond: the contribution of gut microbial-derived metabolites. Gut Microbes, 12 (1). Art. 1810531.

Kurbatova, N., Garg, M., Whiley, L.ORCID: 0000-0002-9088-4799, Chekmeneva, E., Jiménez, B., Gómez-Romero, M., Pearce, J., Kimhofer, T., D’Hondt, E., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Aarsland, D., Nevado-Holgado, A., Liu, B., Snowden, S., Proitsi, P., Ashton, N.J., Hye, A., Legido-Quigley, C., Lewis, M.R., Nicholson, J.K., Holmes, E., Brazma, A. and Lovestone, S. (2020) Urinary metabolic phenotyping for Alzheimer’s disease. Scientific Reports, 10 (1). Art. 21745.

Yeung, D., Penney, N., Whiley, L.ORCID: 0000-0002-9088-4799, Ashrafian, H., Purkayastha, S., Holmes, E. and Darzi, A. (2019) A389 Kynurenic Acid- A clue for different mechanisms of action in Bariatric surgery? Surgery for Obesity and Related Diseases, 15 (10). S158.

Shen, E.Y-L, Abellona, U., Taylor-Robinson, S., Thursz, M., Holmes, E. and Nicholson, J. (2019) Abstract 5269: Discovery and validation of plasma acylcarnitines for the early diagnosis of hepatocellular carcinoma. Cancer Research, 79 (13). p. 5269.

Seow, W.J., Shu, X-O, Nicholson, J.K., Holmes, E., Walker, D.I., Hu, W., Cai, Q., Gao, Y-T, Xiang, Y-B, Moore, S.C., Bassig, B.A., Wong, J.Y.Y., Zhang, J., Ji, B-T, Boulangé, C.L., Kaluarachchi, M., Wijeyesekera, A., Zheng, W., Elliott, P., Rothman, N. and Lan, Q. (2019) Association of untargeted urinary metabolomics and lung cancer risk among never-smoking women in China. JAMA Network Open, 2 (9).

Byrne, C.S., Chambers, E.S., Preston, T., Tedford, C., Brignardello, J., Garcia-Perez, I., Holmes, E., Wallis, G.A., Morrison, D.J. and Frost, G.S. (2019) Effects of inulin propionate Ester Incorporated into palatable food products on appetite and resting energy expenditure: A randomised crossover study. Nutrients, 11 (4). p. 861.

Onida, S., Tan, M.K.H., Kafeza, M., Bergner, R.T., Shalhoub, J., Holmes, E. and Davies, A.H. (2019) Metabolic phenotyping in venous disease: The need for standardization. Journal of Proteome Research, 18 (11). pp. 3809-3820.

Kundu, P., Lee, H.U., Garcia-Perez, I., Tay, E.X.Y., Kim, H., Faylon, L.E., Martin, K.A., Purbojati, R., Drautz-Moses, D.I., Ghosh, S., Nicholson, J.K., Schuster, S., Holmes, E. and Pettersson, S. (2019) Neurogenesis and prolongevity signaling in young germ-free mice transplanted with the gut microbiota of old mice. Science Translational Medicine, 11 (518).

Gibson, R., Lau, C-H.E, Loo, R.L., Ebbels, T.M.D., Chekmeneva, E., Dyer, A.R., Miura, K., Ueshima, H., Zhao, L., Daviglus, M.L., Stamler, J., Van Horn, L., Elliott, P., Holmes, E. and Chan, Q. (2019) The association of fish consumption and its urinary metabolites with cardiovascular risk factors: The International Study of Macro-/Micronutrients and Blood Pressure (INTERMAP). The American Journal of Clinical Nutrition, 111 (2). pp. 280-290.

Lahiri, S., Kim, H., Garcia-Perez, I., Reza, M.M., Martin, K.A., Kundu, P., Cox, L.M., Selkrig, J., Posma, J.M., Zhang, H., Padmanabhan, P., Moret, C., Gulyás, B., Blaser, M.J., Auwerx, J., Holmes, E., Nicholson, J., Wahli, W. and Pettersson, S. (2019) The gut microbiota influences skeletal muscle mass and function in mice. Science Translational Medicine, 11 (502).

Everett, J.R., Holmes, E., Veselkov, K.A., Lindon, J.C. and Nicholson, J.K. (2019) A unified conceptual framework for metabolic phenotyping in diagnosis and prognosis. Trends in Pharmacological Sciences, 40 (10). pp. 763-773.

Westwood, S., Hye, A., Lleó, A., Nevado-Holgado, A.J., Baird, A.L., Wallin, A., Leslie, A., Jimenez, B., Liu, B.Y., Legido-Quigley, C., Dima, D., Ruvolo, D., Holmes, E., D'Hondt, E., Westman, E., Barkhof, F., Frisoni, G.B., Zetterberg, H., Bos, I., Pearce, J., Streffer, J., Molinuevo, J.L., Popp, J., Bertram, L., Whiley, L.ORCID: 0000-0002-9088-4799, Maslen, L., Gómez-Romero, M., David, M., Lewis, M., Kurbatova, N., Ashton, N.J., Voyle, N., Kowalczyk, O., Martinez-Lage, P., Proitsi, P., Scheltens, P., Visser, P.J., Dobson, R.J.B., Vandenberghe, R., Engelborghs, S., Vos, S.J.B., Snowden, S.G., Athersuch, T., Ashby, T., Kimhofer, T., Verachtert, W. and Lovestone, S. (2017) Discovery and validation of multimodal biomarker signatures relating to Alzheimer's disease pathology and progression. Alzheimer's & Dementia, 13 (7). P174-P175.