Publications: Ham, Kristin

Journal Article

Ham, K.A.ORCID: 0000-0002-7036-5334, Aung-Htut, M.T., Fletcher, S. and Wilton, S.D. (2020) Nonsequential splicing events alter antisense-mediated exon skipping outcome in COL7A1. International Journal of Molecular Sciences, 21 (20). Article 7705.

Aung-Htut, M.T., Ham, K.A.ORCID: 0000-0002-7036-5334, Tchan, M.C., Fletcher, S. and Wilton, S.D. (2020) Novel mutations found in individuals with adult-onset Pompe disease. Genes, 11 (2). Article 135.

Aung-Htut, M.T., Ham, K.A.ORCID: 0000-0002-7036-5334, Tchan, M., Johnsen, R., Schnell, F.J., Fletcher, S. and Wilton, S.D. (2020) Splice modulating antisense oligonucleotides restore some acid-alpha-glucosidase activity in cells derived from patients with late-onset Pompe disease. Scientific Reports, 10 . Article number: 6702.

Li, D., Aung-Htut, M.T., Ham, K.A.ORCID: 0000-0002-7036-5334, Fletcher, S. and Wilton, S.D. (2020) A splice intervention therapy for autosomal recessive juvenile Parkinson’s disease arising from Parkin mutations. International Journal of Molecular Sciences, 21 (19). Article 7282.

Aung-Htut, M.T., McIntosh, C.S., West, K.A.ORCID: 0000-0002-7036-5334, Fletcher, S. and Wilton, S.D. (2019) In vitro validation of phosphorodiamidate morpholino oligomers. Molecules, 24 (16). Article 2922.

Aung-Htut, M.T., McIntosh, C.S., Ham, K.A.ORCID: 0000-0002-7036-5334, Pitout, I.L., Flynn, L.L., Greer, K., Fletcher, S. and Wilton, S.D. (2019) Systematic approach to developing splice modulating antisense oligonucleotides. International Journal of Molecular Sciences, 20 (20). Article 5030.

West, K.A.ORCID: 0000-0002-7036-5334, Fletcher, S. and Wilton, S.D. (2018) Antisense oligonnucleotide treatment of COL7A1 causes non-specific splice modifications. Journal of Gene Medicine, 20 (1). e3003.

Matthews, V., Candy, P.A., West, K.A.ORCID: 0000-0002-7036-5334, Knuckey, N.W., Robbins, P., Jeffcote, T. and Boulos, S. (2018) CYPA and CD147 expression analysis in human glioblastoma: Evidence for a correlation with reduced survival. Journal of Translational Science, 4 (5). pp. 1-7.

Aung-Htut, M.T., West, K.ORCID: 0000-0002-7036-5334, Barrett, L., Cardwell, K., Schnell, F.J., Fletcher, S. and Wilton, S.D. (2018) Late onset Pompe disease: Rescue of acid alpha-glucosidase expression by splice modification. Journal of Gene Medicine, 20 (1).

Li, D., Greer, K., West, K.ORCID: 0000-0002-7036-5334, Addams, A., Fletcher, S. and Wilton, S. (2018) Small chemical modulation of induced alternative splicing. Journal of Gene Medicine, 20 (1).

West, K.A.ORCID: 0000-0002-7036-5334, Barrett, L., Fletcher, S. and Wilton, S.D. (2015) Comparison of three different mutations in DMD exon 40 that influence the efficiency of AO induced exon skipping. The Journal of Gene Medicine, 17 (8-9). PO10.

Wilton, S., Adams, A., Greer, K., West, K.A.ORCID: 0000-0002-7036-5334 and Fletcher, S. (2015) Therapeutic alternative splicing: an update on Duchenne muscular dystrophy clinical trials and other applications. The Journal of Gene Medicine, 17 (8 - 9). O19.

Greene, I.D., Mastaglia, F., Meloni, B.P., West, K.A.ORCID: 0000-0002-7036-5334, Chieng, J., Mitchell, C.J., Gai, W-P and Boulos, S. (2013) Evidence that the LRRK2 ROC domain Parkinson's disease-associated mutants A1442P and R1441C exhibit increased intracellular degradation. Journal of Neuroscience Research, 92 (4). pp. 506-516.

Non-refereed Article

Ham, K.ORCID: 0000-0002-7036-5334, Keegan, N., McIntosh, C., Aung-Htut, M., Zaw, K., Greer, K., Fletcher, S. and Wilton, S. (2021) Cryptic U2-dependent Pre-mRNASplice site usage induced by splice switching antisense oligonucleotides. Research Square . In Review.