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Cranking the immunologic engine with chemotherapy: Using context to drive tumor antigen cross-presentation towards useful antitumor immunity

van der Most, R.G., Currie, A., Robinson, B.W.S. and Lake, R.A. (2006) Cranking the immunologic engine with chemotherapy: Using context to drive tumor antigen cross-presentation towards useful antitumor immunity. Cancer Research, 66 (2). pp. 601-604.

Free to read: http://dx.doi.org/10.1158/0008-5472.CAN-05-2967
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Abstract

This review shows how tumor antigen cross-presentation is affected by the major therapeutic modalities including chemotherapy, radiotherapy, and surgery. We argue that this process could affect the way that a tumor works as its own cellular vaccine, and that it is differentially modulated by the choice of treatment.

Item Type: Journal Article
Publisher: American Association for Cancer Research
Copyright: ©2006 American Association for Cancer Research.
URI: http://researchrepository.murdoch.edu.au/id/eprint/9551
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