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The molecular epidemiology of penicillin-susceptible Staphylococcus aureus bacteraemia in Australia and the reliability of diagnostic phenotypic susceptibility method to detect penicillin susceptibility

Yee, Nicholas Wei Tek (2022) The molecular epidemiology of penicillin-susceptible Staphylococcus aureus bacteraemia in Australia and the reliability of diagnostic phenotypic susceptibility method to detect penicillin susceptibility. Honours thesis, Murdoch University.

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Abstract

Staphylococcus was first identified by Sir Alexander Ogston in 1881 when he was investigating the cause of suppurative inflammation in post-operative human patients. Using a light microscope, Ogston observed the spherical nature of the bacterium arranged in clusters in pus collected from an abscess. He was able to demonstrate the bacterium was the cause of the abscess by injecting healthy guinea pigs with pus, which resulted in septicaemia with the presence of the bacterium in blood (1). Conceived by Ogston, the term ‘Staphylococcus’ is from the Greek words “staphyle” (σταφύλια) meaning grapes, and “kokkos” (κόκκος) meaning berry (2). The species name of Staphylococcus aureus, derived from the Latin word “aurum” for gold, was subsequently coined by Friedrich Julius Rosenbach due to the distinct golden yellow pigmented colonies produced by the bacterium (3).

Item Type: Thesis (Honours)
Murdoch Affiliation(s): Medical, Molecular and Forensic Sciences
Supervisor(s): Coombs, Geoffrey, Mowlaboccus, Shakeel and Mullally, Christopher
URI: http://researchrepository.murdoch.edu.au/id/eprint/65614
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