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Anti-Golgi antibody as a potential indicator for rheumatoid arthritis

Zhai, J., Liao, J., Wang, M., Huang, Z., Hu, J., Xu, H., Xie, Q., Ma, B., Baan, C.C. and Wu, Y. (2021) Anti-Golgi antibody as a potential indicator for rheumatoid arthritis. Laboratory Medicine, 53 (2). pp. 156-160.

Free to read: https://doi.org/10.1093/labmed/lmab046
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Abstract

Objective

To reveal the relationship between anti-Golgi antibody (AGA) and clinical diseases through retrospective analysis.

Methods

The clinical data of 584 cases testing positive for AGA in the past 11 years were collected and retrospectively analyzed.

Results

AGA pattern accounted for .2% of positive ANA results. In total, 35.0% of diagnosed patients had autoimmune diseases (AID), mainly rheumatoid arthritis (RA). High-titer AGA (≧1:1000) was common in AID. In nondiagnosed patients with clinical symptoms, joint pain/muscle pain was the most common.

Conclusions

Positive AGA with high titer was closely related to RA. Joint pain/muscle pain was the most common symptom in patients who tested AGA positive. Therefore, AGA may be a key indicator of RA in the Chinese population.

Item Type: Journal Article
Murdoch Affiliation(s): School of Veterinary and Life Sciences
Publisher: Oxford Academic
Copyright: © 2022 American Society for Clinical Pathology
URI: http://researchrepository.murdoch.edu.au/id/eprint/64190
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