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Association and expression analysis of porcine HNF1A gene related to meat and carcass quality traits

Kayan, A., Uddin, M.J., Kocamis, H., Tesfaye, D., Looft, C., Tholen, E., Schellander, K. and Çınar, M.U. (2013) Association and expression analysis of porcine HNF1A gene related to meat and carcass quality traits. Meat Science, 94 (4). pp. 474-479.

Link to Published Version: https://doi.org/10.1016/j.meatsci.2013.04.015
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Abstract

The aim of this study was to investigate the association and expression of HNF1A gene as a candidate gene for meat and carcass quality traits in pigs. Statistical analysis revealed that the g.8260 A>G polymorphism significantly associated with pH 24H, meat percentage and muscle area in the F2 Duroc × Pietrain (DuPi, n = 313) and with pH 24L, fat area and backfat thickness in the Pietrain (Pi, n = 110) population. HNF1A mRNA and protein expressions were higher (p < 0.05) in animals with the low post-mortem muscle pH 24L. The promoter methylation profiling suggested that methylation was not involved on HNF1A expression regulation (p > 0.05) in animal with divergent muscle pH. In conclusion, polymorphism in porcine HNF1A gene could be used as a candidate marker to improve the meat and carcass quality traits, with the consideration of breed-specific effect.

Item Type: Journal Article
Publisher: Elsevier BV
Copyright: © 2013 Elsevier Ltd.
URI: http://researchrepository.murdoch.edu.au/id/eprint/62600
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