Murdoch University Research Repository

Welcome to the Murdoch University Research Repository

The Murdoch University Research Repository is an open access digital collection of research
created by Murdoch University staff, researchers and postgraduate students.

Learn more

Diffuse large B cell lymphoma within an anal fistula: a case report with an intriguing possible aetiology

Kent, J., Joske, D. and Parry, J. (2021) Diffuse large B cell lymphoma within an anal fistula: a case report with an intriguing possible aetiology. Journal of Surgical Case Reports, 2021 (8). Art. rjab360.

[img]
Preview
PDF - Published Version
Download (703kB) | Preview
Free to read: https://doi.org/10.1093/jscr/rjab360
*No subscription required

Abstract

Described is a case of diffuse large B cell lymphoma that presented within a typical fistula tract, possibly secondary to oxidative stress within the fistula tract itself and consequent malignant change rather than a fistula as a consequence of necrosis in a lymphoma. If so it would be unique in the world literature. A 42-year-old fitness instructor presented with a typical appearing left lateral anal fistula. Biopsy of the fistulous tract revealed B cell lymphoma, graded 1E. Although chemotherapy cured the lymphoma, surgical treatment by ligation of the inter-sphincteric fistula tract was required to heal the fistula. At 3-year follow-up, there has been no recurrence of the lymphoma or the fistula. Neoplasia arising secondary to oxidative stress within an anal fistula is a well-established phenomenon. Early diagnosis of rare conditions associated with anal fistula can only be accomplished by routine biopsy of every fistula tract.

Item Type: Journal Article
Publisher: JSCR Publishing Ltd
Copyright: © 2021 Oxford University Press and JSCR Publishing Ltd
URI: http://researchrepository.murdoch.edu.au/id/eprint/62077
Item Control Page Item Control Page

Downloads

Downloads per month over past year