Murdoch University Research Repository

Welcome to the Murdoch University Research Repository

The Murdoch University Research Repository is an open access digital collection of research
created by Murdoch University staff, researchers and postgraduate students.

Learn more

Garenoxacin

Robinson, J.O. and Christiansen, K. (2017) Garenoxacin. In: Grayson, M.L., Cosgrove, S.E., Crowe, S.E., Hope, W., McCarthy, J.S., Mills, J., Mouton, J.W. and Paterson, D.L., (eds.) Kucers’ The Use of Antibiotics: A Clinical Review of Antibacterial, Antifungal, Antiparasitic, and Antiviral Drugs. CRC Press.

Link to Published Version: https://doi.org/10.1201/9781498747967
*Subscription may be required

Abstract

Garenoxacin is a des-fluoro(6) quinolone that, as such, lacks a fluorine at the C-6 position in comparison with other fluoroquinolones such as ciprofloxacin, moxifloxacin, and levofloxacin, and has a difluoromethoxy substitution at position C-8 (Fung-Tomc et al., 2000). The molecular formula is 1-cyclopropyl-8-(difluoromethoxy)-7-[(1R)-(1-methyl-2, 3-dihydro-1H-5-isoindolyl)-4-oxo-1, 4-dihydro-3-quinoline-carboxylic acid methanesulfonate monohydrate (Takahata et al., 1999) (see Figure 114.1). Figure 114.1 Chemical structure of garenoxacin.

Item Type: Book Chapter
Publisher: CRC Press
URI: http://researchrepository.murdoch.edu.au/id/eprint/61646
Item Control Page Item Control Page