Murdoch University Research Repository

Welcome to the Murdoch University Research Repository

The Murdoch University Research Repository is an open access digital collection of research
created by Murdoch University staff, researchers and postgraduate students.

Learn more

Comparison of survival after surgical or medical treatment in dogs with a congenital portosystemic shunt

Greenhalgh, S.N., Dunning, M.D., McKinley, T.J., Goodfellow, M.R., Kelman, K.R.ORCID: 0000-0002-4877-3112, Freitag, T., O'Neill, E.J., Hall, E.J., Watson, P.J. and Jeffery, N.D. (2010) Comparison of survival after surgical or medical treatment in dogs with a congenital portosystemic shunt. Journal of the American Veterinary Medical Association, 236 (11). pp. 1215-1220.

PDF - Published Version
Download (394kB) | Preview
Free to read:
*No subscription required


Objective—To compare survival of dogs with a congenital portosystemic shunt (CPSS) that received medical or surgical treatment.

Design—Prospective cohort study.

Animals—126 client-owned dogs with a single CPSS.

Procedures—Dogs were examined at 1 of 3 referral clinics, and a single CPSS was diagnosed in each. Dogs received medical or surgical treatment without regard to signalment, clinical signs, or results of hematologic or biochemical analysis. Survival data were analyzed via a Cox regression model.

Results—During a median follow-up period of 579 days, 18 of 126 dogs died as a result of CPSS. Dogs treated via surgical intervention survived significantly longer than did those treated medically. Hazard ratio for medical versus surgical treatment of CPSS (for the treatment-only model) was 2.9 (95% confidence interval, 1.1 to 7.2). Age at CPSS diagnosis did not affect survival.

Conclusions and Clinical Relevance—Both medical and surgical treatment can be used to achieve long-term survival of dogs with CPSS, although results of statistical analysis supported the widely held belief that surgery is preferable to medical treatment. However, the study population consisted of dogs at referral clinics, which suggested that efficacy of medical treatment may have been underestimated. Although surgical intervention was associated with a better chance of long-term survival, medical management provided an acceptable first-line option. Age at examination did not affect survival, which implied that early surgical intervention was not essential. Dogs with CPSS that do not achieve acceptable resolution with medical treatment can subsequently be treated surgically.

Item Type: Journal Article
Publisher: American Veterinary Medical Association (AVMA)
Item Control Page Item Control Page


Downloads per month over past year