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The current situation of diagnosis and treatment of neuromyelitis optica spectrum disorder: Experience with 461 cases from a single centre in South China

Li, C., Wang, J., Sun, X., Li, R., Chang, Y., Wang, Y., Zhong, X., Kermode, A.G., Mao, Z. and Qiu, W. (2021) The current situation of diagnosis and treatment of neuromyelitis optica spectrum disorder: Experience with 461 cases from a single centre in South China. Journal of Neuroimmunology, 353 . Art. 577506.

Link to Published Version: https://doi.org/10.1016/j.jneuroim.2021.577506
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Abstract

In this study, we included 461 NMOSD patients at our hospital from January 2016 to June 2019 and got some results. Eight (1.9%) originally AQP4-IgG-seronegative patients were retested as seropositive. 221 patients (47.9%) did not receive immunosuppressive treatment within 3 month. The adult/child distribution was significantly different ( p = 0.001). Thirty-three patients (7.2%) had relapses after drug withdrawal, and fifteen of them had used drugs ≥3 years. The conclusion is that decision to treat with immunosuppression was made less often in children than in adults. Patients who took medication for a long time still need to be cautious of stopping using immunosuppression.

Item Type: Journal Article
Murdoch Affiliation(s): Institute for Immunology and Infectious Diseases
Publisher: Elsevier
Copyright: © 2021 Elsevier Inc.
URI: http://researchrepository.murdoch.edu.au/id/eprint/59636
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