Murdoch University Research Repository

Welcome to the Murdoch University Research Repository

The Murdoch University Research Repository is an open access digital collection of research
created by Murdoch University staff, researchers and postgraduate students.

Learn more

Molecular characterization of a novel, serologically detectable, HLA-C allele: Cw∗1602

Vilches, C., Herrero, M.J., de Pablo, R., Moreno, M.E., Bunce, M. and Kreisler, M. (1994) Molecular characterization of a novel, serologically detectable, HLA-C allele: Cw∗1602. Human Immunology, 41 (2). pp. 167-170.

Link to Published Version: http://dx.doi.org/10.1016/0198-8859(94)90011-6
*Subscription may be required

Abstract

Cw∗1602, a novel HLA-C allele belonging to the newly assigned Cw∗16 group, has been cloned and sequenced from a Spanish Caucasoid cell expressing a “Cw6.2” phenotype. Some of the polymorphic substitutions of the new allele, and linkage disequilibrium to B51, had been predicted on the basis of previously published studies. The primary structure of Cw∗1602 is in agreement with its serologic reactivity and, in comparison with that of Cw∗1601, underlines the dimorphism of HLA-C molecules at residues 77 and 80 of the α1-domain α helix.

Item Type: Journal Article
Publisher: Elsevier BV
Copyright: 1994 Elsevier Inc.
URI: http://researchrepository.murdoch.edu.au/id/eprint/5890
Item Control Page Item Control Page