Evaluation of 13 rapidly mutating Y-STRs on a Dravidian pedigree
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Iyavoo, S., Alghafri, R.
ORCID: 0000-0002-8321-9678, Almheiri, R. and Haizel, T.
(2019)
Evaluation of 13 rapidly mutating Y-STRs on a Dravidian pedigree.
Forensic Science International: Genetics Supplement Series, 7
(1).
pp. 216-217.
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Abstract
The effectiveness of a rapidly mutating Y-STRs multiplex assay (RM Y-STRs) containing 13 RM Y-STR markers was compared with the AmpFℓSTR™ Yfiler™ PCR Amplification Kit (Yfiler) with conventional Y-STR markers for their efficiency in differentiating males within the same paternal lineage. Samples from 4 generations comprising 16 Dravidian males (15 father-son pairs) were analysed with both assays. Mutations were observed in 3 father-son pairs in the RM Y-STRs profiles while only 2 mutations were observed in the Y-filer profiles. Even though not many mutations were observed as anticipated, this study still emphasised the importance of RM Y-STRs when differentiation between males within the same paternal lineage is required and also indicated the need for mutation rates for different populations.
| Item Type: | Journal Article |
|---|---|
| Publisher: | Elsevier |
| Copyright: | © 2019 Elsevier B.V. |
| URI: | http://researchrepository.murdoch.edu.au/id/eprint/58482 |
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