Genetically modified ruminal bacteria protect sheep from fluoroacetate poisoning

Gregg, K., Hamdorf, B., Henderson, K., Kopecny, J. and Wong, C.M. (1998) Genetically modified ruminal bacteria protect sheep from fluoroacetate poisoning. Applied and Environmental Microbiology, 64 (9). pp. 3496-3498.

Abstract

Four strains of Butyrivibrio fibrisolvens, transformed with a gene encoding fluoroacetate dehalogenase, maintained a combined population of 10(6) to 10(7) cells ml-1 in the rumens of test sheep. Five inoculated sheep showed markedly reduced toxicological symptoms after fluoroacetate poisoning when behavioral, physiological, and histological effects were compared with those of five uninoculated control sheep.

Item Type:	Journal Article
Murdoch Affiliation(s):	Western Australian State Agricultural Biotechnology Centre
Publisher:	American Society for Microbiology
Copyright:	1998 American Society for Microbiology
URI:	http://researchrepository.murdoch.edu.au/id/eprint/5648

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