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Investigation of a Lomentospora prolificans case cluster with whole genome sequencing

Boan, P., Pang, S., Gardam, D.J., Darragh, H., Wright, M. and Coombs, G.W.ORCID: 0000-0003-1635-6506 (2020) Investigation of a Lomentospora prolificans case cluster with whole genome sequencing. Medical Mycology Case Reports, 29 . pp. 1-4.

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Lomentospora prolificans has caused outbreaks in immunocompromised patients. We performed whole genome sequencing (WGS) on 4 L. prolificans isolates from infections occurring during an 8-month period in the haematology unit at Hospital 1., and 2 isolates from unrelated infections at Hospital 2., showing a high number of mutational differences (>10,000 single nucleotide polymorphisms) between L. prolificans isolates from Hospital 1. Novel typing of isolates by WGS did not demonstrate a single causative strain.

Item Type: Journal Article
Murdoch Affiliation(s): Medical, Molecular and Forensic Sciences
Publisher: Elsevier B.V.
Copyright: © 2020 The Authors.
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