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Current and developing methods for diagnosing Alzheimer's disease

Fuller, S.J., Carrigan, N., Sohrabi, H.R.ORCID: 0000-0001-8017-8682 and Martins, R.N. (2019) Current and developing methods for diagnosing Alzheimer's disease. In: Martins, R.N., Brennan, C.S., Fernando, W.M.A.D.B., Brennan, M.A. and Fuller, S.J., (eds.) Neurodegeneration and Alzheimer's Disease: The Role of Diabetes, Genetics, Hormones, and Lifestyle. John Wiley and Sons Ltd, pp. 43-87.

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Although Alzheimer's disease (AD) is the most common cause of dementia in the elderly, a definite diagnosis of AD normally requires post‐mortem examination. Without specialised brain scans and other tests that are currently only used for clinical research purposes, the many diagnostic tests that are presently available only result in a diagnosis of ‘probable’ AD. These diagnostic tests are also very time‐consuming. This chapter briefly describes the classical post‐mortem findings in an AD brain, then discusses the wide variety of current neuropsychological tests, followed by current and developing imaging and biomarker‐based clinical diagnostic methods.

Item Type: Book Chapter
Publisher: John Wiley and Sons Ltd
Copyright: © 2019 John Wiley & Sons Ltd
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