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Acute necrotising pulmonary vasculitis and pulmonary hypertension in a juvenile dog

Russell, N.J., Irwin, P.J.ORCID: 0000-0002-0006-8262, Hopper, B.J., Olivry, T. and Nicholls, P.K.ORCID: 0000-0001-7071-3055 (2008) Acute necrotising pulmonary vasculitis and pulmonary hypertension in a juvenile dog. Journal of Small Animal Practice, 49 (7). pp. 349-355.

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A five-month-old female Jack Russell terrier was presented for investigation of acute lethargy, anorexia, coughing, respiratory distress and weakness. Examination findings included cyanosis, a grade 3 of 6 systolic heart murmur and prolonged capillary refill time. Radiography and echocardiography revealed severe pulmonary hypertension, cor pulmonale and right-sided heart failure. Indirect measurement of the systolic pulmonary artery pressure estimated pressures over 100 mmHg. Despite treatment the patient died. Postmortem examination did not identify a congenital cardiovascular anomaly. Histopathology confirmed acute necrotising pulmonary arteritis and immunohistochemistry failed to identify any immune complex or complement deposition.

Item Type: Journal Article
Murdoch Affiliation(s): School of Veterinary and Biomedical Sciences
Publisher: Blackwell Publishing
Copyright: © 2008 British Small Animal Veterinary Association.
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