Murdoch University Research Repository

Welcome to the Murdoch University Research Repository

The Murdoch University Research Repository is an open access digital collection of research
created by Murdoch University staff, researchers and postgraduate students.

Learn more

Associations between LSAMP gene polymorphisms and major depressive disorder and panic disorder

Koido, K., Traks, T., Balõtšev, R., Eller, T., Must, A., Kõks, S., Maron, E., Tõru, I., Shlik, J., Vasar, V. and Vasar, E. (2012) Associations between LSAMP gene polymorphisms and major depressive disorder and panic disorder. Translational Psychiatry, 2 (8). e152-e152.

[img]
Preview
PDF - Published Version
Download (529kB) | Preview
Free to read: https://doi.org/10.1038/tp.2012.74
*No subscription required

Abstract

The purpose of this case–control genetic association study was to explore potential relationships between polymorphisms in the limbic system-associated membrane protein (LSAMP) gene and mood and anxiety disorders. A total of 21 single-nucleotide polymorphisms (SNPs) from the LSAMP gene were analyzed in 591 unrelated patients with the diagnoses of major depressive disorder (MDD) or panic disorder (PD) and in 384 healthy control subjects. The results showed a strong association between LSAMP SNPs and MDD, and a suggestive association between LSAMP SNPs and PD. This is the first evidence of a possible role of LSAMP gene in mood and anxiety disorders in humans.

Item Type: Journal Article
Publisher: Macmillan Publishers Limited
Copyright: 2012 Macmillan Publishers Limited
URI: http://researchrepository.murdoch.edu.au/id/eprint/51781
Item Control Page Item Control Page

Downloads

Downloads per month over past year