Murdoch University Research Repository

Welcome to the Murdoch University Research Repository

The Murdoch University Research Repository is an open access digital collection of research
created by Murdoch University staff, researchers and postgraduate students.

Learn more

Diagnosis of melioidosis by means of an ELISA detecting antibodies to Pseudomonas pseudomallei exotoxin. Preliminary assay evaluation

Smith, C.J., Jones, M.ORCID: 0000-0001-5002-0227, Dance, D.A.B., Chaowagul, W. and White, N.J. (1991) Diagnosis of melioidosis by means of an ELISA detecting antibodies to Pseudomonas pseudomallei exotoxin. Preliminary assay evaluation. World Journal of Microbiology and Biotechnology, 7 (1). pp. 29-36.

Link to Published Version: https://doi.org/10.1007/BF02310916
*Subscription may be required

Abstract

An ELISA system for the detection of human antibodies toPseudomonas pseudomallei exotoxin is described. Analysis of control sera and sera from patients with culture-positive melioidosis showed that both IgG and IgM antibodies to exotoxin were detectable in patients with melioidosis. This implies that the exotoxin is producedin vivo byP. pseudomallei, and may be involved in the pathogenesis of melioidosis. Furthermore, these rapid and simple assays may prove to be useful for the serodiagnosis of the disease.

Item Type: Journal Article
Publisher: Springer Verlag
Copyright: © 1991 Rapid Communications of Oxford Ltd
URI: http://researchrepository.murdoch.edu.au/id/eprint/49629
Item Control Page Item Control Page