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Derivatisation of chemical warfare agent degradant without removal of water

Chua, Xiang Le (2018) Derivatisation of chemical warfare agent degradant without removal of water. Masters by Coursework thesis, Murdoch University.

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Degradation products are distinct chemical signature for the detection of chemical warfare agents and forensic attribution in cases where the parent compound no longer exists. Being the common degradant to nerve agents, methylphosphonic acid serves as an explicit biomarker for the use of nerve agents. However, this non-volatile compound requires derivatisation prior to its detection, which incurs time-limiting factor and error. Therefore, development for a novel rapid and simple approach for identifying these degradants is of high importance to shed light on the use of chemical warfare agents and remediation of impacts. With the success of a recent pilot study for derivatisation of methylphosphonic acid without elimination of water, a subsequent quantitative study can be proceeded to assess on its practicality and efficiency.

Item Type: Thesis (Masters by Coursework)
Murdoch Affiliation(s): School of Veterinary and Life Sciences
United Nations SDGs: Goal 3: Good Health and Well-Being
Goal 16: Peace, Justice and Strong Institutions
Supervisor(s): Rowen, Kate and Coumbaros, John
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