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Decreased physical working capacity in adolescents with Non-Alcoholic fatty liver disease reflects reduced iron bioavailability

Mitchell, T., McKinnon, E., Ayonrinde, O.T., Adams, L.A., Trinder, D., Chua, A., Newton, R., Strakers, L. and Olynyk, J.K. (2018) Decreased physical working capacity in adolescents with Non-Alcoholic fatty liver disease reflects reduced iron bioavailability. Hepatology, 68 . 1317A-1318A.

Free to read: https://doi.org/10.1002/hep.30257
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Abstract

Background: Non-alcoholic fatty liver disease (NAFLD) is a common, chronic liver disorder related to obesity and insulin resistance. Iron metabolism is impaired in obese patients, often despite elevated serum ferritin levels. In healthy patients, iron deficiency has been associated with physical inactivity, however little is known regarding the relationship between iron metabolism and reduced physical capacity in individuals with NAFLD. We aimed to determine firstly, whether there was an association between iron bioavailability, as measured by mean cell volume (MCV) and transferrin saturation (TSAT), and physical work capacity, and secondly, whether NAFLD influenced this relationship…

Item Type: Journal Article
Murdoch Affiliation: Institute for Immunology and Infectious Diseases
Publisher: John Wiley & Sons Inc.
Copyright: © 2018 by the American Association for the Study of Liver Diseases.
Other Information: Poster abstract
URI: http://researchrepository.murdoch.edu.au/id/eprint/42373
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