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The transcriptional landscape of polyploid wheat

Ramirez-Gonzalez, R.H., Borrill, P., Lang, D., Harrington, S.A., Brinton, J., Venturini, L., Davey, M., Jacobs, J., van Ex, F., Pasha, A., Khedikar, Y., Robinson, S.J., Cory, A.T., Florio, T., Concia, L., Juery, C., Schoonbeek, H., Steuernagel, B., Xiang, D., Ridout, C.J., Chalhoub, B., Mayer, K.F.X., Benhamed, M., Latrasse, D., Bendahmane, A., Wulff, B.B.H., Appels, R., Tiwari, V., Datla, R., Choulet, F., Pozniak, C.J., Provart, N.J., Sharpe, A.G., Paux, E., Spannagl, M., Bräutigam, A. and Uauy, C. (2018) The transcriptional landscape of polyploid wheat. Science, 361 (6403).

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Wheat is one of the major sources of food for much of the world. However, because bread wheat's genome is a large hybrid mix of three separate subgenomes, it has been difficult to produce a high-quality reference sequence. Using recent advances in sequencing, the International Wheat Genome Sequencing Consortium presents an annotated reference genome with a detailed analysis of gene content among subgenomes and the structural organization for all the chromosomes. Examples of quantitative trait mapping and CRISPR-based genome modification show the potential for using this genome in agricultural research and breeding. Ramírez-González et al. exploited the fruits of this endeavor to identify tissue-specific biased gene expression and coexpression networks during development and exposure to stress. These resources will accelerate our understanding of the genetic basis of bread wheat.

Item Type: Journal Article
Murdoch Affiliation(s): School of Veterinary and Life Sciences
Publisher: American Association for the Advancement of Science
Copyright: © 2018 American Association for the Advancement of Science
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