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Giardia duodenalis mouse model for the development of novel antigiardial agents

Abraham, R.J., O'Dea, M.ORCID: 0000-0002-2757-7585, Rusdi, B., Page, S.W., O'Handley, R. and Abraham, S. (2018) Giardia duodenalis mouse model for the development of novel antigiardial agents. Journal of Microbiological Methods, 145 . pp. 7-9.

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Link to Published Version: https://doi.org/10.1016/j.mimet.2017.11.025
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Abstract

This study describes a neonatal mouse model of Giardia infection for development of novel antigiardials. Mice were infected with the axenically cultured Assemblage A BAH2c2 strain, with 105 trophozoites per animal recovered. This model proved to be robust and consistent for use in preliminary drug efficacy trials and drug development.

Item Type: Journal Article
Murdoch Affiliation(s): School of Veterinary and Life Sciences
Publisher: Elsevier BV
Copyright: © 2017 Published by Elsevier B.V
URI: http://researchrepository.murdoch.edu.au/id/eprint/39957
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