Murdoch University Research Repository

Welcome to the Murdoch University Research Repository

The Murdoch University Research Repository is an open access digital collection of research
created by Murdoch University staff, researchers and postgraduate students.

Learn more

Serum paraoxonase-1 activity in neonatal calves: Age related variations and comparison between healthy and sick animals

Giordano, A., Veronesi, M.C., Rossi, G.ORCID: 0000-0003-4879-9504, Pezzia, F., Probo, M., Giori, L. and Paltrinieri, S. (2013) Serum paraoxonase-1 activity in neonatal calves: Age related variations and comparison between healthy and sick animals. The Veterinary Journal, 197 (2). pp. 499-501.

Link to Published Version: https://doi.org/10.1016/j.tvjl.2013.01.034
*Subscription may be required

Abstract

Early detection of inflammation in neonatal calves allows early intervention, which may reduce mortality. Paraoxonase-1 (PON1) is a negative acute phase protein in humans. The aims of this study were to investigate age-related variability in serum PON1 activity and its clinical usefulness in neonatal calves. In healthy calves (n= 9), PON1 activity increased with age from 2 to 21. days of age. There was no significant increase in PON1 activity in healthy calves from days 21 to 120 (n= 15), but PON1 activity was significantly higher in adult cattle (n= 45). In sick calves, serum PON1 was significantly lower in calves <7. days of age with diarrhoea (n= 8) and in calves >28- to 120-days-old with respiratory disease (n= 8) in comparison with age matched controls (n= 20 and n= 15, respectively). These results support the role of PON1 as a negative acute phase protein in cattle.

Item Type: Journal Article
Publisher: Balliere Tindall
Copyright: © 2013 Elsevier Ltd.
URI: http://researchrepository.murdoch.edu.au/id/eprint/38941
Item Control Page Item Control Page