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Innate and adaptive immunity shape circulating HCV strains

Gaudieri, S. and Lucas, M. (2017) Innate and adaptive immunity shape circulating HCV strains. Nature Genetics, 49 (5). pp. 657-658.

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An unbiased genome-to-genome analysis in chronic hepatitis C virus (HCV) infection confirms the innate and adaptive arms of the immune system as drivers of viral evolution. Viral adaptation has a critical role in the interaction between host and pathogen and has important clinical implications for infection outcome.

Item Type: Journal Article
Murdoch Affiliation(s): Institute for Immunology and Infectious Diseases
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