Approaches to the synthesis of 4-hydroxypiloquinone
Tools
Tools
Giles, R.G.F., Mitchell, P.R.K. and Sargent, M.V. (1983) Approaches to the synthesis of 4-hydroxypiloquinone. Journal of the Chemical Society, Perkin Transactions 1 . pp. 2147-2152.
*Subscription may be required
Abstract
The synthesis of 4-acetoxy-1,8-dihydroxy-2-methyl-3-(4-methylpentanoyl)phenanthrene-9,10-quinoee (30) and 1,4,8-trimethoxy-2-methyl-3-(4-methylpentanoyl)phenanthrene-9,10-quinone (33), derivatives of the mould metabolite 4-hydroxypiloquinone [1,4,8-trihydroxy-2-methyl-3-(4-methylpentanoyl)-phenanthrene-9,10-quinone](2) are described. Photocyclization of methyl 2,2′,5,6′-tetramethoxy-3-methylstilbene-4-carboxylate (21) provided methyl 1,4,8-trimethoxy-2-methylphenanthrene-3-carboxylate (22), suitable for further elaboration into the natural derivatives.
| Item Type: | Journal Article |
|---|---|
| Publisher: | Royal Society of Chemistry |
| Copyright: | © 1983 Royal Society of Chemistry |
| URI: | http://researchrepository.murdoch.edu.au/id/eprint/35668 |
 |
Item Control Page |
