Role of the MexAB-OprM Efflux Pump of Pseudomonas aeruginosa in tolerance to tea tree (Melaleuca alternifolia) oil and its monoterpene components terpinen-4-ol, 1,8-Cineole, and α-Terpineol ∇
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Papadopoulos, C.J., Carson, C.F., Chang, B.J. and Riley, T.V. (2008) Role of the MexAB-OprM Efflux Pump of Pseudomonas aeruginosa in tolerance to tea tree (Melaleuca alternifolia) oil and its monoterpene components terpinen-4-ol, 1,8-Cineole, and α-Terpineol ∇. Applied and Environmental Microbiology, 74 (6). pp. 1932-1935.
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Abstract
Using a series of efflux mutants of Pseudomonas aeruginosa, the MexAB-OprM pump was identified as contributing to this organism's tolerance to the antimicrobial agent tea tree (Melaleuca alternifolia) oil and its monoterpene components terpinen-4-ol, 1,8-cineole, and α-terpineol. These data show that a multidrug efflux system of P. aeruginosa can extrude monoterpenes and related alcohols.
| Publication Type: | Journal Article |
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| Publisher: | American Society for Microbiology |
| Copyright: | © 2008 American Society for Microbiology |
| URI: | http://researchrepository.murdoch.edu.au/id/eprint/35367 |
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