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Amygdala volumetric change following psychotherapy for posttraumatic stress disorder

Laugharne, J., Kullack, C., Lee, C.W., McGuire, T.M., Brockman, S., Drummond, P.D.ORCID: 0000-0002-3711-8737 and Starkstein, S. (2016) Amygdala volumetric change following psychotherapy for posttraumatic stress disorder. The Journal of Neuropsychiatry and Clinical Neurosciences, 28 (4). pp. 312-318.

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The authors investigated the impact of eye movement desensitization and reprocessing (EMDR) and prolonged exposure (PE) on the volumes of the amygdala and hippocampus, structures known to be important in fear conditioning, in 20 patients with posttraumatic stress disorder (PTSD). Patients were randomly allocated to either EMDR or PE. Volumes were assessed before and after treatment via magnetic resonance imaging (MRI). Both groups showed significant improvements in PTSD symptoms. Left amygdala mean volume increased significantly following EMDR treatment only. No significant volumetric changes were found for the hippocampus.

Item Type: Journal Article
Murdoch Affiliation(s): School of Psychology and Exercise Science
Publisher: American Psychiatric Publishing
Copyright: © 2016 American Psychiatric Association
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