Pycnanthuquinone C, an unusual 6,6,5-tricyclic geranyltoluquinone from the Western Australian brown alga Cystophora harveyi
Laird, D.W.ORCID: 0000-0001-7550-4607, Poole, R., Wikström, M. and van Altena, I.A.
(2007)
Pycnanthuquinone C, an unusual 6,6,5-tricyclic geranyltoluquinone from the Western Australian brown alga Cystophora harveyi.
Journal of Natural Products, 70
(4).
pp. 671-674.
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Abstract
Chemical investigation of the Western Australian marine brown alga Cystophora harveyi resulted in the isolation of the new linearly fused 6,6,5-tricyclic compound pycnanthuquinone C (1), in addition to four previously reported geranyltoluquinol derivatives. Structures were elucidated by interpretation of spectrometric data. Compounds with the same cyclic skeleton as 1 have been reported to be useful drug leads for the treatment of type 2 diabetes, while compounds 4 and 7 are known constituents of Chinese medicinal herbs. A biosynthetic scheme encompassing all of the geranyltoluquinol derivatives isolated from C. harveyi is proposed.
Item Type: | Journal Article |
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Murdoch Affiliation(s): | School of Chemical and Mathematical Science |
Publisher: | American Chemical Society |
Copyright: | © 2007 American Chemical Society and American Society of Pharmacognosy. |
URI: | http://researchrepository.murdoch.edu.au/id/eprint/3451 |
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