Murdoch University Research Repository

Welcome to the Murdoch University Research Repository

The Murdoch University Research Repository is an open access digital collection of research
created by Murdoch University staff, researchers and postgraduate students.

Learn more

Halogenated cyclic peptides isolated from the sponge Corticium sp.

Laird, D.W.ORCID: 0000-0001-7550-4607, LaBarbera, D.V., Feng, X., Bugni, T.S., Harper, M.Kay and Ireland, C.M. (2007) Halogenated cyclic peptides isolated from the sponge Corticium sp. Journal of Natural Products, 70 (5). pp. 741-746.

Link to Published Version:
*Subscription may be required


Fractionation of two Fijian specimens of the sponge Corticium sp. led to the isolation of the known active alkaloid steroid plakinamine A and two new halogenated cyclic peptides, corticiamide A (1) and cyclocinamide B (2). Structural elucidation of 1 and 2 was achieved by an extensive combination of high-field NMR and HRFT MS/MS experiments, and the absolute stereochemistry of 2 was determined by acid hydrolysis and Marfey's analysis. Corticiamide A (1) and cyclocinamide B (2) represent the first peptides to be described from the genus Corticium.

Item Type: Journal Article
Publisher: American Chemical Society
Copyright: © 2007 American Chemical Society and American Society of Pharmacognosy
Item Control Page Item Control Page