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Halogenated cyclic peptides isolated from the sponge Corticium sp.

Laird, D.W.ORCID: 0000-0001-7550-4607, LaBarbera, D.V., Feng, X., Bugni, T.S., Harper, M.Kay and Ireland, C.M. (2007) Halogenated cyclic peptides isolated from the sponge Corticium sp. Journal of Natural Products, 70 (5). pp. 741-746.

Link to Published Version: http://dx.doi.org/10.1021/np060489v
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Abstract

Fractionation of two Fijian specimens of the sponge Corticium sp. led to the isolation of the known active alkaloid steroid plakinamine A and two new halogenated cyclic peptides, corticiamide A (1) and cyclocinamide B (2). Structural elucidation of 1 and 2 was achieved by an extensive combination of high-field NMR and HRFT MS/MS experiments, and the absolute stereochemistry of 2 was determined by acid hydrolysis and Marfey's analysis. Corticiamide A (1) and cyclocinamide B (2) represent the first peptides to be described from the genus Corticium.

Item Type: Journal Article
Publisher: American Chemical Society
Copyright: © 2007 American Chemical Society and American Society of Pharmacognosy
URI: http://researchrepository.murdoch.edu.au/id/eprint/3450
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