The effect of sodium monofluoroacetate on plasma testosterone concentration in Tiliqua rugosa (gray)

Twigg, L.E., King, D.R. and Bradley, A.J. (1988) The effect of sodium monofluoroacetate on plasma testosterone concentration in Tiliqua rugosa (gray). Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, 91 (2). pp. 343-347.

Abstract

1. 1. Administration of multiple or single doses of sodium fluoroacetate (1080) to male Tiliqua rugosa caused a decrease in plasma testosterone concentration. 2. 2. A single dose of 100 or 250 mg 1080 kg-1 body weight decreased plasma testosterone by 52%. However, 25 mg kg-1 had little apparent effect on testosterone levels. When lizards were given the multiple dose equivalent of these doses over 12 days at 3 day intervals, the effect was much less dramatic with plasma testosterone concentration steadily declining over 15 days for the two higher doses. 3. 3. There was a suggestion of degeneration of seminiferous tubules in some individuals

Item Type:	Journal Article
Murdoch Affiliation(s):	School of Environmental and Life Sciences
Publisher:	Elsevier BV
URI:	http://researchrepository.murdoch.edu.au/id/eprint/34264

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