Murdoch University Research Repository

Welcome to the Murdoch University Research Repository

The Murdoch University Research Repository is an open access digital collection of research
created by Murdoch University staff, researchers and postgraduate students.

Learn more

Prevalence of Clostridium difficile colonization among healthcare workers

Friedman, N.D., Pollard, J., Stupart, D., Knight, D.R.ORCID: 0000-0002-9480-4733, Khajehnoori, M., Davey, E.K, Parry, L. and Riley, T.V. (2013) Prevalence of Clostridium difficile colonization among healthcare workers. BMC Infectious Diseases, 13 . Article number: 459.

PDF - Published Version
Available under License Creative Commons Attribution.

Download (183kB) | Preview
Free to read:
*No subscription required


Clostridium difficile infection (CDI) has increased to epidemic proportions in recent years. The carriage of C. difficile among healthy adults and hospital inpatients has been established. We sought to determine whether C. difficile colonization exists among healthcare workers (HCWs) in our setting.

A point prevalence study of stool colonization with C. difficile among doctors, nurses and allied health staff at a large regional teaching hospital in Geelong, Victoria. All participants completed a short questionnaire and all stool specimens were tested by Techlab® C.diff Quik Check enzyme immunoassay followed by enrichment culture.

Among 128 healthcare workers, 77% were female, of mean age 43 years, and the majority were nursing staff (73%). Nineteen HCWs (15%) reported diarrhoea, and 12 (9%) had taken antibiotics in the previous six weeks. Over 40% of participants reported having contact with a patient with known or suspected CDI in the 6 weeks before the stool was collected. C. difficile was not isolated from the stool of any participants.

Although HCWs are at risk of asymptomatic carriage and could act as a reservoir for transmission in the hospital environment, with the use of a screening test and culture we were unable to identify C. difficile in the stool of our participants in a non-outbreak setting. This may reflect potential colonization resistance of the gut microbiota, or the success of infection prevention strategies at our institution.

Item Type: Journal Article
Publisher: BioMed Central
Copyright: © Friedman et al.
Item Control Page Item Control Page


Downloads per month over past year