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Inclusion Body Myositis

Mastaglia, F.L. and Needham, M. (2010) Inclusion Body Myositis. In: Lisak, R.P., Truong, D.D., Carroll, W.M. and Bhidayasiri, R., (eds.) International Neurology. Wiley-Blackwell, pp. 474-476.

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inclusion body myositis;
sporadic inclusion body myositis (sIBM) - common myopathy in Caucasians over 50 years of age;
epidemiology and genetic susceptibility;
genetic susceptibility, linked to HLA-DR3 and 8.1 MHC ancestral haplotype (AH) in West Australian cohort;
serum CK level - normal or mildly elevated (up to 10 times normal);
no therapy currently - for stopping disease progression;
intravenous immunoglobulin therapy (IVIG) - short-term benefit in selected cases;
glucocorticoids and cytotoxic agents

Item Type: Book Chapter
Page Range: pp. 474-476
Publisher: Wiley-Blackwell
Copyright: © 2009 Blackwell Publishing Ltd
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