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Sickle cell disease and posterior reversible leukoencephalopathy

Geevasinga, N., Cole, C., Herkes, G.K., Barnett, Y., Lin, J. and Needham, M. (2014) Sickle cell disease and posterior reversible leukoencephalopathy. Journal of Clinical Neuroscience, 21 (8). pp. 1329-1332.

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Sickle cell disease can present with neurological manifestations. One such presentation is with posterior reversible leukoencephalopathy also known as reversible posterior leukoencephalopathy. The condition is classically described as reversible over time; it commonly presents with oedematous changes involving the white matter of the occipital and parietal regions. Only a few patients with the association between sickle cell disease and posterior reversible leukoencephalopathy have been described in the adult literature. We present two patients from our institutions to emphasise the association between the two conditions and summarise the published cases in the literature.

Item Type: Journal Article
Publisher: Churchill Livingstone
Copyright: © 2014 Elsevier Ltd.
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