Divergent Inflammatory, Fibrogenic, and Liver Progenitor Cell Dynamics in Two Common Mouse Models of Chronic Liver Injury
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Köhn-Gaone, J., Dwyer, B.J., Grzelak, C.A., Miller, G., Shackel, N.A., Ramm, G.A., McCaughan, G.W., Elsegood, C.L., Olynyk, J.K. and Tirnitz-Parker, J.E.E. (2016) Divergent Inflammatory, Fibrogenic, and Liver Progenitor Cell Dynamics in Two Common Mouse Models of Chronic Liver Injury. The American Journal of Pathology, 186 (7). pp. 1762-1774.
Link to Published Version: http://dx.doi.org/10.1016/j.ajpath.2016.03.005
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Abstract
Complications of end-stage chronic liver disease signify a major cause of mortality worldwide. Irrespective of the underlying cause, most chronic liver diseases are characterized by hepatocellular necrosis, inflammation, fibrosis, and proliferation of liver progenitor cells or ductular reactions...
| Item Type: | Journal Article |
|---|---|
| Murdoch Affiliation: | School of Veterinary and Life Sciences |
| Journal or Publication Title: | The American Journal of Pathology |
| Page Range: | pp. 1762-1774 |
| Publisher: | Elsevier |
| Copyright: | © 2016 American Society for Investigative Pathology. |
| URI: | http://researchrepository.murdoch.edu.au/id/eprint/32360 |
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