Murdoch University Research Repository

Welcome to the Murdoch University Research Repository

The Murdoch University Research Repository is an open access digital collection of research
created by Murdoch University staff, researchers and postgraduate students.

Learn more

Hybridization based enrichment for genotyping HLA and KIR genes using Next Generation Sequencing

Cooper, D., Chopra, A., Blinco, J., Leary, S., Watson, M.ORCID: 0000-0002-6438-9225 and Mallal, S. (2015) Hybridization based enrichment for genotyping HLA and KIR genes using Next Generation Sequencing. In: Science on the Swan, 21 - 23 April 2015, Perth, Western Australia.

[img]
Preview
PDF (Poster)
Download (822kB) | Preview

Abstract

Several disease association studies indicate that, the interactions between the KIR and HLA loci may have a role in infectious diseases, autoimmune disorders, cancer and reproduction. Current typing methods for HLA Loci use PCR for whole gene amplification or selected exon amplification. The Killer cell immunoglobulin-like receptors (KIR) genes are polymorphic and the gene complex is polygenic with a varying number of inhibitory (iKIRs) and activating (aKIRs) receptors. Due to this complexity of the KIR locus, genotyping is not performed as routinely.

Item Type: Conference Item
Murdoch Affiliation: Institute for Immunology and Infectious Diseases
Conference Website: http://www.scienceontheswan.com.au/
URI: http://researchrepository.murdoch.edu.au/id/eprint/31889
Item Control Page Item Control Page

Downloads

Downloads per month over past year