Murdoch University Research Repository

Welcome to the Murdoch University Research Repository

The Murdoch University Research Repository is an open access digital collection of research
created by Murdoch University staff, researchers and postgraduate students.

Learn more

Extraintestinal colonisation by Serpulina pilosicoli in an experimentally inoculated pig

Hampson, D.J.ORCID: 0000-0002-7729-0427, Robertson, I.D.ORCID: 0000-0002-4255-4752 and Oxberry, S.L. (1998) Extraintestinal colonisation by Serpulina pilosicoli in an experimentally inoculated pig. In: 15th International Pig Veterinary Society Congress, 5 - 9 July, Birmingham, UK p. 54.

PDF - Published Version
Download (89kB) | Preview


The intestinal spirochaete Serpulina pilosicoli colonises the porcine large intestine where characteristically, but not invariably, large numbers of these bacteria become attached by one cell end to the mucosa (4). This colonisation can induce a colitis and a diarrhoeal disease called intestinal spirochaetosis (IS). Besides pigs, IS occurs naturally in various species of birds, as well as in dogs and human beings. Recently, S. pilosicoli was isolated from the bloodstream of a series of debilitated and/or immunocompromised human patients, some of whom subsequently died (5). It is not known whether S. pilosicoli can also invade and colonise extraintestinal sites in pigs, whether immunosupression would be necessary for this to occur, nor what the clinical outcomes might be. The current experiment was undertaken to investigate these possibilities, using pigs inoculated intravenously with the spirochaete so as to maximise the opportunity for colonisation to occur.

Item Type: Conference Paper
Murdoch Affiliation(s): School of Veterinary and Biomedical Sciences
Item Control Page Item Control Page


Downloads per month over past year