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Comparative in vitro sensitivity of Serpulina hyodysenteriae and Serpilona pilosicoli isolates to six antimicrobials

Oxberry, S.L. and Hampson, D.J.ORCID: 0000-0002-7729-0427 (1998) Comparative in vitro sensitivity of Serpulina hyodysenteriae and Serpilona pilosicoli isolates to six antimicrobials. In: 15th International Pig Veterinary Society Congress, 5 - 9 July, Birmingham, UK p. 132.

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The pathogenic intestinal spirochaetes Serpulina hyodysenteriae and Serpulina pilosicoli are the respective agents of swine dysentery (SD) and porcine intestinal spirochaetosis (PIS). Swine dysentery is a severe mucohaemorrhagic colitis, while PIS is a less severe diarrhoeal disease causing reduced growth rates and loss of condition. SD and PIS are both common diseases in Australia, and cause major production losses.

Control of SD and PIS on infected piggeries relies heavily on the use of antimicrobial agents. For this reason, comprehensive in vitro antimicrobial sensitivity studies have been performed on isolates of S. hyodysenteriae (2,6, 4, 1). Unfortunately, because S. pilosicoli has only recently been described, very little information has been gathered on susceptibility of isolates of this species. Previous studies have investigated the antimicrobial sensitivities of uncharacterised weakly B-haemolytic intestinal spirochaetes (3), however it is now realised that these are likely to have included several species of the genus Serpulina, some of which are pathogenic and some apparently benign. The purpose of this work was to make a comparative study of the antimicrobial sensitivities of a range of isolates of S. hyodysenteriae and S. pilosicoli.

Item Type: Conference Paper
Murdoch Affiliation(s): School of Veterinary and Biomedical Sciences
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