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Carbapenemase-producing bacteria in companion animals: A public health concern on the horizon

Abraham, S., Wong, H.S., Turnidge, J., Johnson, J.R. and Trott, D.J. (2014) Carbapenemase-producing bacteria in companion animals: A public health concern on the horizon. Journal of Antimicrobial Chemotherapy, 69 (5). pp. 1155-1157.

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Clinical infections attributed to carbapenemase-producing bacteria are a pressing public health concern owing to limited therapeutic options and linked antimicrobial resistance. In recent years, studies have reported the emergence and spread of carbapenemase-producing Enterobacteriaceae and their public health impact. This has been closely followed by the global dissemination of highly resistant and virulent zooanthroponotic extraintestinal pathogenic Escherichia coli (ExPEC) ST131 clones. It has also been hypothesized that companion animals may act as a reservoir for Gram-negative multidrug-resistant pathogens in the community. Two recent reports have documented the emergence of carbapenemase-producing bacteria in companion animals. This phenomenon is of great concern because of the close contact between humans and their pets, and the potential for cross-species transmission. This scenario suggests a role for multifaceted control of Gram-negative multidrugresistant infections in companion animals. This short article addresses this issue and identifies steps that could facilitate this process.

Item Type: Journal Article
Publisher: Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy
Copyright: © The Author 2014
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