Murdoch University Research Repository

Welcome to the Murdoch University Research Repository

The Murdoch University Research Repository is an open access digital collection of research
created by Murdoch University staff, researchers and postgraduate students.

Learn more

Seizures due to multiple sclerosis: Seven patients with MRI correlations

Thompson, A.J., Kermode, A.G., Moseley, I.F., MacManus, D.G. and McDonald, W.I. (1993) Seizures due to multiple sclerosis: Seven patients with MRI correlations. Journal of Neurology, Neurosurgery & Psychiatry, 56 (12). pp. 1317-1320.

Link to Published Version:
*Subscription may be required
Free to read:
*No subscription required


The MRI data of seven patients with clinically definite multiple sclerosis who developed epileptic seizures are presented. Six of these cases demonstrated new or enhancing lesions. Cerebral biopsy in one of these lesions confirmed inflammation with myelin breakdown products. Lesions implicated in the causation of seizures involved the cortex or subcortical area. In one patient, a new lesion was associated with EEG abnormalities which resolved as the lesion reduced in size. In three patients epileptic activity was the only clinical manifestation of disease. Large, unresolving lesions tended to be associated with continuing seizures.

Item Type: Journal Article
Publisher: BMJ Publishing Group
Copyright: © 1993 by the BMJ Publishing Group Ltd
Item Control Page Item Control Page