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Community-onset Gram-negative Surveillance Program annual report, 2012

Turnidge, J.D., Gottlieb, T., Mitchell, D.H., Coombs, G.W.ORCID: 0000-0003-1635-6506, Daley, D.A. and Bell, J.M. for the Australian Group on Antimicrobial Resistance (2014) Community-onset Gram-negative Surveillance Program annual report, 2012. Communicable diseases intelligence quarterly report, 38 (1). E49-E53.

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The Australian Group on Antimicrobial Resistance performs regular period-prevalence studies to monitor changes in antimicrobial resistance in selected enteric Gram-negative pathogens. The 2011 survey focussed on hospital-onset infections, examining isolates from all specimens presumed to be causing disease. In 2011, 1,827 Escherichia coli, 537 Klebsiella species and 269 Enterobacter species were tested using a commercial automated method (Vitek 2, BioMérieux) and results were analysed using Clinical and Laboratory Standards Institute breakpoints from January 2012. Of the key resistances, non-susceptibilty to the third-generation cephalosporin, ceftriaxone, was found in 9.6% of E. coli and 9.5%–12.1% ofKlebsiella spp. Non-susceptibility rates to ciprofloxacin were 10.6% for E. coli, 0.0%–8.3% for Klebsiella spp. and 0.0%–5.0% in Enterobacter spp. Resistance rates to gentamicin were 8.6%, 2.9%–10.9%, and 0.0%–15.6% for the same 3 groups respectively. Eight strains, 5 Klebsiella spp. and 3 Enterobacter spp. were shown to harbour a carbapenemase (IMP-4).

Item Type: Journal Article
Publisher: Department of Health, Australia
Copyright: ©
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