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Selenium enriched pork may reduce colon carcinogenesis

Jayasooriya, S.D., Ponnampalam, E.N., Pluske, J.R.ORCID: 0000-0002-7194-2164, Gill, H., McIntosh, G.H. and Dunshea, F.R. (2009) Selenium enriched pork may reduce colon carcinogenesis. In: Manipulating Pig Production XII. Proceedings of the 12th Australasian Pig Science Association (APSA) Biennial Conference, 22 - 25 November, Werribee, Australia p. 94.

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Extensive experimental evidence indicates that selenium (Se) supplementation reduces the incidence of cancer in animals (Hu et al., 2008). However, the delivery of Se is challenging due to its toxicity, especially when consumed in an inorganic form. The consumption of Se enriched pork where the Se is bound in an organic protein matrix could provide a means of delivering direct health benefits for humans (Biesalski, 2002). This study investigated the effectiveness of Se enriched pork in the suppression of aberrant crypt foci (ACF) formation, the putative precursors of colon cancer (Bird and Good, 2000), using a rodent azoxymethane (AOM) induced colon cancer model.

Item Type: Conference Paper
Murdoch Affiliation(s): School of Veterinary and Biomedical Sciences
Publisher: Australasian Pig Science Association
Copyright: © 2009 Australasian Pig Science Association (Inc)
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