Longitudinal evaluation of cardiovascular disease-associated biomarkers in relation to abacavir therapy

Hammond, E.L., McKinnon, E., Mallal, S. and Nolan, D. (2008) Longitudinal evaluation of cardiovascular disease-associated biomarkers in relation to abacavir therapy. AIDS, 22 (18). pp. 2540-2543.

Abstract

This study provides a longitudinal evaluation of biomarkers of cardiovascular relevance during abacavir therapy in previously treatment-naı¨ve patients as well as treatment experienced patients with HIV infection. We evaluated levels of D-dimer, as well as highly sensitive C reactive protein (hs-CRP), IL-6, IL-8, tumour necrosis factor (TNF)a, monocyte chemoattractant protein (MCP-1), hepatocyte growth factor (HGF) [5–8], as well as adiponectin and leptin [9,10], as inflammatory and metabolic markers potentially relevant to cardiovascular disease.

Item Type:	Journal Article
Murdoch Affiliation:	Centre for Clinical Immunology and Biomedical Statistics
Publisher:	Lippincott Williams & Wilkins Ltd.
URI:	http://researchrepository.murdoch.edu.au/id/eprint/2839

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