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A review of major histocompatibility complex-disease associations in man and dog

Day, M.J. and Penhale, W.J. (1987) A review of major histocompatibility complex-disease associations in man and dog. Veterinary Research Communications, 11 (2). pp. 119-132.

Link to Published Version: http://dx.doi.org/10.1007/BF00344944
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Abstract

The organization and biology of the Major Histocompatibility Complexes (MHC) of man (HLA) and dog (DLA) are reviewed, and a summary is presented of laboratory techniques used to define allotypes. The nomenclature of this field and the mechanisms of disease association with the MHC are discussed. Currently recognized HLA-disease associations are enumerated, with emphasis on the value of the complement C4 marker. DLA-disease association studies into autoimmune disease, allergy and neoplasia are reviewed.

Item Type: Journal Article
Murdoch Affiliation: School of Veterinary Studies
Publisher: Springer Netherlands
Copyright: © 1987 Geo Abstracts Ltd.
URI: http://researchrepository.murdoch.edu.au/id/eprint/20790
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