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Humoral immunity in disseminated Aspergillus terreus infection in the dog

Day, M.J. and Penhale, W.J. (1988) Humoral immunity in disseminated Aspergillus terreus infection in the dog. Veterinary Microbiology, 16 (3). pp. 283-94.

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Aspects of humoral immunity were studied in 17 dogs with disseminated aspergillosis (16 cases Aspergillus terreus, 1 case Aspergillus flavipes). All dogs had markedly raised serum IgG levels by single radial immunodiffusion (range 1500-6000 mg dl-1). Despite this, serum antibody to A. terreus was demonstrated in only 7/16 cases by agar gel diffusion, 9/16 cases by counter immunoelectrophoresis, 10/16 by ELISA and 11/16 by an indirect immunofluorescence assay. Serum antibody was also detected in 2/5 clinically normal relatives of 2 cases, indicating previous exposure or subclinical infection.

Item Type: Journal Article
Murdoch Affiliation(s): School of Veterinary Studies
Publisher: Elsevier BV
Copyright: © 1988 Published by Elsevier B.V.
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