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Iron overload in blacks: Ironing out the issues

Fortun, P.J., Griffiths, A. and Olynyk, J.K. (2003) Iron overload in blacks: Ironing out the issues. The American Journal of Gastroenterology, 98 (7). pp. 1456-1458.

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Since the identification of mutations in the hemochromatosis (HFE) gene that are responsible for hereditary hemochromatosis (HH) (1) our understanding of disorders of iron metabolism and the relationship between genotype and phenotype has advanced considerably. In Western countries, most iron overload is caused by mutations in the HFE gene and occurs predominantly in whites, with an incidence of up to one in 200 (2).

Item Type: Journal Article
Publisher: Nature Publishing Group
Copyright: 2003 The American College of Gastroenterology
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